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Research at St Andrews

Alan J. Stewart

Person

  1. Patent › Research
  2. Published

    Design of mutated forms of human serum albumin with altered metal binding characteristics for pharmacological or cell culture uses.

    Berezenko, S., Sadler, P. J., Stewart, A. J., Blindauer, C. A. & Bunyan, K. E., 5 Feb 2004, IPC No. C07K 14/765 (2006.01), Patent No. WO/2004/011499

    Research output: Patent

  3. Article › Research › Not peer-reviewed
  4. Published

    Plasma non-esterified fatty acids contribute to increased coagulability in type-2 diabetes through altered plasma zinc speciation

    Sobczak, A. I. S., Katundu, K. G. H., Phoenix, F. A., Khazaipoul, S., Yu, R., Lampiao, F., Stefanowicz, F., Blindauer, C. A., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., 28 Aug 2019, In : biorxiv. 38 p.

    Research output: Contribution to journalArticle

  5. Published

    Putative roles for phospholipase C-η enzymes in neuronal Ca2+ signal modulation.

    Popovics, P. & Stewart, A. J., 1 Feb 2012, In : Biochemical Society Transactions. 40, p. 282-286 5 p.

    Research output: Contribution to journalArticle

  6. Article › Research › Peer-reviewed
  7. Published

    17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats

    Zafirovic, S., Obradovic, M., Sudar-Milovanovic, E., Jovanovic, A., Stanimirovic, J., Stewart, A. J., Pitt, S. J. & Isenovic, E. R., 5 May 2017, In : Molecular and Cellular Endocrinology. 446, p. 12-20 9 p.

    Research output: Contribution to journalArticle

  8. Published

    In vivo effects of 17β-estradiol on cardiac Na+/K+-ATPase expression and activity in rat heart

    Obradovic, M., Stewart, A. J., Pitt, S. J., Labudovic-Borovic, M., Sudar, E., Petrovic, V., Zafirovic, S., Maravic-Stojkovic, V., Vasic, V. & Isenovic, E. R., 5 May 2014, In : Molecular and Cellular Endocrinology. 388, 1-2, p. 58-68

    Research output: Contribution to journalArticle

  9. Published

    A canonical EF-loop directs Ca2+-sensitivity in phospholipase C-η2

    Popovics, P., Lu, J., Kamil, L. N., Morgan, K., Millar, R. P., Schmid, R., Blindauer, C. A. & Stewart, A. J., 1 Mar 2014, In : Journal of Cellular Biochemistry. 115, 3, p. 557–565 9 p.

    Research output: Contribution to journalArticle

  10. Published

    A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats

    Stanimirovic, J., Obradovic, M., Jovanovic, A., Sudar-Milovanovic, E., Zafirovic, S., Pitt, S. J., Stewart, A. J. & Isenovic, E. R., 1 Apr 2016, In : Nitric Oxide. 54, p. 51-59 9 p.

    Research output: Contribution to journalArticle

  11. Published

    A metalloproteomic analysis of interactions between plasma proteins and zinc: elevated fatty acid levels affect zinc distribution

    Coverdale, J. P. C., Barnett, J. P., Adamu, A. H., Griffiths, E. J., Stewart, A. J. & Blindauer, C. A., 1 Nov 2019, In : Metallomics. 11, 11, p. 1805-1819 15 p.

    Research output: Contribution to journalArticle

  12. Published

    A molecular mechanism for modulating plasma Zn speciation by fatty acids

    Lu, J., Stewart, A. J., Sleep, D., Sadler, P. J., Pinheiro, T. J. T. & Blindauer, C. A., 25 Jan 2012, In : Journal of the American Chemical Society. 134, 3, p. 1454-1457 4 p.

    Research output: Contribution to journalArticle

  13. Published

    A role for inositol monophosphatase 1 (IMPA1) in salinity adaptation in the euryhaline eel (Anguilla anguilla)

    Kalujnaia, S., McVee, J., Kasciukovic, T., Stewart, A. J. & Cramb, G., Oct 2010, In : FASEB Journal. 24, p. 3981-3991 11 p.

    Research output: Contribution to journalArticle

  14. Published

    Albumin as a zinc carrier: properties of its high-affinity zinc-binding site

    Lu, J., Stewart, A. J., Sadler, PJ., Pinheiro, TJT. & Blindauer, CA., Dec 2008, In : Biochemical Society Transactions. 36, 6, p. 1317-1321 5 p.

    Research output: Contribution to journalArticle

  15. Published

    Allosteric inhibition of cobalt binding to albumin by fatty acids: Implications for the detection of myocardial ischemia

    Lu, J., Stewart, A. J., Sadler, P. J., Pinheiro, T. J. T. & Blindauer, C. A., 10 May 2012, In : Journal of Medicinal Chemistry. 55, 9, p. 4425-4430 6 p.

    Research output: Contribution to journalArticle

  16. Published

    Allosteric modulation of zinc speciation by fatty acids

    Barnett, J. P., Blindauer, C. A., Kassaar, O., Khazaipoul, S., Martin, E. M., Sadler, P. J. & Stewart, A. J., Dec 2013, In : Biochimica et Biophysica Acta - General Subjects. 1830, 12, p. 5456-5464 9 p.

    Research output: Contribution to journalArticle

  17. Published

    Antiproliferative effects of GnRH agonists: prospects and problems for cancer therapy

    White, CD., Stewart, A. J., Lu, ZL., Millar, RP. & Morgan, K., Aug 2008, In : Neuroendocrinology. 88, 2, p. 67-79 13 p.

    Research output: Contribution to journalArticle

  18. Published

    Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet

    Jovanovic, A., Obradovic, M., Sudar-Milovanovic, E., Stewart, A. J., Pitt, S. J., Alvantic, D., Aleksic, E. & Isenovic, E. R., Dec 2017, In : Molecular and Cellular Biochemistry. 436, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalArticle

  19. Published

    Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins

    Handing, K. B., Shabalin, I. G., Kassaar, O., Khazaipoul, S., Blindauer, C. A., Stewart, A. J., Chruszcz, M. & Minor, W., 1 Nov 2016, In : Chemical Science. 7, 11, p. 6635-6648 14 p.

    Research output: Contribution to journalArticle

  20. Published

    Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily

    Stewart, A. J., Schmid, R., Blindauer, CA., Paisey, SJ. & Farquharson, C., Dec 2003, In : Protein Engineering. 16, 12, p. 889-895 7 p.

    Research output: Contribution to journalArticle

  21. Published

    Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: implications for angiogenic regulation

    Kassaar, O., McMahon, S. A., Thompson, R., Botting, C. H., Naismith, J. H. & Stewart, A. J., 20 Mar 2014, In : Blood. 123, 12, p. 1948-1955 8 p.

    Research output: Contribution to journalArticle

  22. Published

    Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells: Implications for luteolysis

    Dickinson, R. E., Stewart, A. J., Myers, M., Millar, R. P. & Duncan, W. C., Jun 2009, In : Endocrinology. 150, 6, p. 2873-2881 9 p.

    Research output: Contribution to journalArticle

  23. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In : Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticle

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