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Research at St Andrews

David Christopher Crossman

Person

  1. 2019
  2. Published

    A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

    Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M., Morrell, N. W. & 7 others, Crossman, D. C., Whyte, M. K. B., Stenmark, K. R., Newman, C. M., Kiely, D. G., Francis, S. E. & Lawrie, A., 15 Nov 2019, In: Nature Communications. 10, 18 p., 5183.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial

    Mullen, M., Jin, X. Y., Child, A., Stuart, A. G., Dodd, M., Aragon-Martin, J. A., Gaze, D., Kiotsekoglou, A., Yuan, L., Hu, J., Foley, C., Van Dyck, L., Knight, R., Clayton, T., Swan, L., Thomson, J. D. R., Erdem, G., Crossman, D., Flather, M. & AIMS Investigators, 21 Dec 2019, In: Lancet. 394, 10216, p. 2263-2270

    Research output: Contribution to journalArticlepeer-review

  4. 2018
  5. Published

    ATP evokes Ca2+ responses and CXCL5 secretion via P2X4 receptor activation in human monocyte-derived macrophages

    Layhadi, J. A., Turner, J., Crossman, D. & Fountain, S. J., 1 Feb 2018, In: The Journal of Immunology. 200, 3, p. 1159-1168

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Canakinumab for atherosclerotic disease

    MRC-ILA Heart investigators, Rothman, A. M., Morton, A. C. & Crossman, D. C., 11 Jan 2018, In: New England Journal of Medicine. 378, 2, p. 197-8 2 p.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Dietary docosahexaenoic acid reduces oscillatory wall shear stress, atherosclerosis and hypertension, most likely mediated via an IL-1-mediated mechanism

    Alfaida, M., Chamberlain, J., Rothman, A., Crossman, D. C., Villa-Uriol, M-C., Hadoke, P., Wu, J., Schenkel, T., Evans, P. & Francis, S., 3 Jul 2018, In: Journal of the American Heart Association. 7, 13, 19 p., e008757.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Interleukin-1 beta inhibition with canakinumab and reducing lung cancer-subset analysis of the canakinumab anti-inflammatory thrombosis outcome study trial (CANTOS)

    Crossman, D. & Rothman, A. M. K., 18 Sep 2018, In: Journal of Thoracic Disease. 10, Suppl 26, p. S3084-S3087

    Research output: Contribution to journalEditorialpeer-review

  9. 2017
  10. Published

    The Canakinumab Antiinflammatory Thrombosis Outcome Study trial-the starting gun has fired

    Crossman, D. & Rothman, A., Dec 2017, In: Journal of Thoracic Disease. 9, 12, p. 4922-4925 4 p.

    Research output: Contribution to journalEditorialpeer-review

  11. 2015
  12. Published

    Anti-inflammatory therapies in myocardial infarction

    Abbate, A., Morton, A. C. & Crossman, D. C., 27 Jun 2015, In: Lancet. 385, 9987, p. 2573-2574 2 p.

    Research output: Contribution to journalLetterpeer-review

  13. Published

    Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis

    Freitag, D., Butterworth, A. S., Willeit, P., Howson, J. M. M., Burgess, S., Kaptoge, S., Young, R., Ho, W. K., Wood, A. M., Sweeting, M., Spackman, S., Staley, J. R., Ramond, A., Harshfield, E., Nielsen, S. F., Grande, P., Lange, L. A., Bown, M. J., Jones, G. T., Scott, R. A. & 133 others, Bevan, S., Porcu, E., Thorleifsson, G., Zeng, L., Kessler, T., Nikpay, M., Do, R., Zhang, W., Hopewell, J. C., Kleber, M., Delgado, G. E., Nelson, C. P., Goel, A., Bis, J. C., Dehghan, A., Ligthart, S., Smith, A. V., Qu, L., van 't Hof, F. N. G., de Bakker, P. I. W., Baas, A. F., van Rij, A., Tromp, G., Kuivaniemi, H., Ritchie, M. D., Verma, S. S., Crawford, D. C., Malinowski, J., de Andrade, M., Kullo, I. J., Peissig, P. L., McCarty, C. A., Böttinger, E. P., Gottesman, O., Crosslin, D. R., Carrell, D. S., Rasmussen-Torvik, L. J., Pacheco, J. A., Huang, J., Timpson, N. J., Kettunen, J., Ala-Korpela, M., Mitchell, G. F., Parsa, A., Wilkinson, I. B., Gorski, M., Li, Y., Franceschini, N., Keller, M. F., Ganesh, S. K., Langefeld, C. D., Bruijn, L., Brown, M. A., Evans, D. M., Baltic, S., Ferreira, M. A., Baurecht, H., Weidinger, S., Franke, A., Lubitz, S. A., Müller-Nurasyid, M., Felix, J. F., Smith, N. L., Sudman, M., Thompson, S. D., Zeggini, E., Panoutsopoulou, K., Nalls, M. A., Singleton, A., Polychronakos, C., Bradfield, J. P., Hakonarson, H., Easton, D. F., Thompson, D., Tomlinson, I. P., Dunlop, M., Hemminki, K., Morgan, G., Eisen, T., Goldschmidt, H., Allan, J. M., Henrion, M., Whiffin, N., Wang, Y., Chubb, D., Iles, M. M., Bishop, D. T., Law, M. H., Hayward, N. K., Luo, Y., Nejentsev, S., Barbalic, M., Crossman, D., Sanna, S., Soranzo, N., Markus, H. S., Wareham, N. J., Rader, D. J., Reilly, M., Assimes, T., Harris, T. B., Hofman, A., Franco, O. H., Gudnason, V., Tracy, R., Psaty, B. M., Farrall, M., Watkins, H., Hall, A. S., Samani, N. J., März, W., Clarke, R., Collins, R., Kooner, J. S., Chambers, J. C., Kathiresan, S., McPherson, R., Erdmann, J., Kastrati, A., Schunkert, H., Stefánsson, K., Thorsteinsdottir, U., Walston, J. D., Tybjærg-Hansen, A., Alam, D. S., Al Shafi Majumder, A., Angelantonio, E. D., Chowdhury, R., Nordestgaard, B. G., Saleheen, D., Thompson, S. G., Danesh, J. & Houlston, R. S., 1 Apr 2015, In: The Lancet Diabetes & Endocrinology. 3, 4, p. 243-253 11 p.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study

    Morton, A. C., Rothman, A. M. K., Greenwood, J. P., Gunn, J., Chase, A., Clarke, B., Hall, A. S., Fox, K., Foley, C., Banya, W., Wang, D., Flather, M. D. & Crossman, D. C., 7 Feb 2015, In: European Heart Journal. 36, 6, p. 377-384 8 p.

    Research output: Contribution to journalArticlepeer-review

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