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Research at St Andrews

David John Hughes

Person

  1. 2017
  2. Published

    Generation of specific inhibitors of SUMO1- and SUMO2/3-mediated protein-protein interactions using Affimer (Adhiron) technology

    Hughes, D. J., Tiede, C., Penswick, N., A. S. Tang, A., Trinh, C. H., Mendal, U., Zajac, K. Z., Gaule, T., Howell, G., Edwards, T. A., Duan, J., Feyfant, E., McPhereson, M. J., Tomlinson, D. C. & Whitehouse, A. 14 Nov 2017 In : Science Signaling. 10, 505, 14 p., eaaj2005

    Research output: Research - peer-reviewArticle

  3. Published

    Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection

    Tang, A. A-S., Tiede, C., Hughes, D. J., McPherson, M. J. & Tomlinson, D. C. 14 Nov 2017 In : Science Signaling. 10, 505, 12 p., eaan0868

    Research output: Research - peer-reviewArticle

  4. 2016
  5. Published

    ARID3B: a novel regulator of the Kaposi’s sarcoma-associated herpesvirus lytic cycle

    Wood, J., Boyne, J., Paulus, C., Jackson, B., Nevels, M. M., Whitehouse, A. & Hughes, D. J. Oct 2016 In : Journal of Virology. 90, 20, p. 9543-9555

    Research output: Research - peer-reviewArticle

  6. 2015
  7. Published

    Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract

    Leeming, G. H., Kipar, A., Hughes, D. J., Bingle, L., Bennett, E., Moyo, N. A., Tripp, R. A., Bigley, A. L., Bingle, C. D., Sample, J. T. & Stewart, J. P. Jun 2015 In : Laboratory Investigation. 95, p. 610-624 15 p.

    Research output: Research - peer-reviewArticle

  8. Published
  9. Published

    NEDDylation is essential for Kaposi’s Sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target

    Hughes, D. J., Wood, J. J., Jackson, B. R., Baquero-Pérez, B. & Whitehouse, A. 20 Mar 2015 In : PLoS Pathogens. 11, 3, 26 p., e1004771

    Research output: Research - peer-reviewArticle

  10. Published

    Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important co-factors that promote L protein stability and RNA synthesis

    Munday, D. C. , Wu, W. , Smith, N. , Fix, J. , Noton, S. L. , Galloux, M. , Touzelet, O. , Armstrong, S. D. , Dawson, J. M. , Aljabr, W. , Easton, A. J. , Rameix-Welti, M-A. , de Oliveira, A. P. , Simabuco, F. , Ventura, A. M. , Hughes, D. J. , Barr, J. N. , Fearns, R. , Digard, P. , Eléouët, J-F. & 1 others Hiscox, J. A. 15 Jan 2015 In : Journal of Virology. 89, 2, p. 917-930 14 p.

    Research output: Research - peer-reviewArticle

  11. 2014
  12. Published

    Utilising proteomic approaches to understand oncogenic human herpesviruses (Review)

    Owen, C. B., Hughes, D. J., Baquero-Perez, B., Berndt, A., Schumann, S., Jackson, B. R. & Whitehouse, A. Nov 2014 In : Molecular and Clinical Oncology. 2, 6, p. 891-903 13 p.

    Research output: Research - peer-reviewArticle

  13. 2012
  14. Published

    CTCF and Sp1 interact with the murine gammaherpesvirus 68 internal repeat elements

    Stevens, H. C., Cham, K. S-W., Hughes, D. J., Sun, R., Sample, J. T., Bubb, V. J., Stewart, J. P. & Quinn, J. P. 2012 In : Virus Genes. 45, 2, p. 265-273

    Research output: Research - peer-reviewArticle

  15. Published

    Contributions of CTCF and DNA Methyltransferases DNMT1 and DNMT3B to Regulation of Epstein-Barr Virus Latency

    Hughes, D. J., Marendy, E. M., Dickerson, C. A., Yetming, K. D., Sample, C. E. & Sample, J. T. 2012 In : Journal of Virology. 86, 2, p. 1034-1045

    Research output: Research - peer-reviewArticle

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