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Research at St Andrews

Frank J Gunn-Moore

Person

  1. 2018
  2. Published

    Alzheimer's disease in humans and other animals: a consequence of postreproductive life span and longevity rather than aging

    Gunn-Moore, D., Kaidanovich-Beilin, O., Gallego Iradi, M. C., Gunn-Moore, F. & Lovestone, S. Feb 2018 In : Alzheimer's and Dementia. 14, 2, p. 195-204

    Research output: Research - peer-reviewArticle

  3. 2017
  4. Published

    In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease

    Aitken, L., Baillie, G., Pannifer, A., Morrison, A., Jones, P. S., Smith, T. K., McElroy, S. P. & Gunn-Moore, F. J. Jul 2017 In : SLAS Discovery. 22, 6, p. 676-685 11 p.

    Research output: Research - peer-reviewArticle

  5. Published

    6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation

    Benek, O., Hroch, L., Aitken, L., Dolezal, R., Guest, P., Benkova, M., Soukup, O., Musil, K., Hughes, R., Kuca, K., Smith, T. K., Gunn-Moore, F. & Musilek, K. Jun 2017 In : Medicinal Chemistry. 13, 4, p. 345-358 14 p.

    Research output: Research - peer-reviewArticle

  6. Published

    Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

    Hroch, L., Guest, P., Benek, O., Soukup, O., Janockova, J., Dolezal, R., Kuca, K., Aitken, L., Smith, T. K., Gunn-Moore, F., Zala, D., Ramsay, R. R. & Musilek, K. 1 Feb 2017 In : Bioorganic & Medicinal Chemistry. 25, 3, p. 1143-1152 10 p.

    Research output: Research - peer-reviewArticle

  7. 2016
  8. Published

    Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells

    Tilston-Lunel, A. M., Haley, K., Schlecht, N., Wang, Y., Chatterton, A. L. D., Moleirinho, S. L., Watson, A., Hundal, H., Prystowsky, M., Gunn-Moore, F. J. & Reynolds, P. A. Oct 2016 In : Journal of Molecular Cell Biology. 8, 5, p. 439-455

    Research output: Research - peer-reviewArticle

  9. Published

    Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system

    Mielenz, D. & Gunn-Moore, F. J. 15 Aug 2016 In : Biochemical Journal. 473, 16, p. 2429-2437

    Research output: Research - peer-reviewReview article

  10. Published

    Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment

    Hroch, L., Benek, O., Guest, P., Aitken, L., Soukup, O., Janockova, J., Musil, K., Dohnal, V., Dolezal, R., Kuca, K., Smith, T. K., Gunn-Moore, F. J. & Musilek, K. 1 Aug 2016 In : Bioorganic and Medicinal Chemistry Letters. 26, 15, p. 3675-3678 4 p.

    Research output: Research - peer-reviewLetter

  11. Published

    Willing to be involved in cancer

    Gunn-Moore, F. J., Tilston-Lunel, A. M. & Reynolds, P. A. 18 Jul 2016 In : Genes. 7, 7, 13 p., 37

    Research output: Research - peer-reviewReview article

  12. Published

    Morphology-specific inhibition of β-amyloid aggregates by 17β-hydroxysteroid dehydrogenase type 10

    Aitken, L., Quinn, S. D., Perez-Gonzalez, D. C., Samuel, I. D. W., Penedo-Esteiro, J. C. & Gunn-Moore, F. J. 2 Jun 2016 In : ChemBioChem. 17, 11, p. 1029-1037

    Research output: Research - peer-reviewArticle

  13. Published

    Visualization of podocyte substructure with structured illumination microscopy (SIM): a new approach to nephrotic disease

    Pullman, J., Nylk, J., Campbell, E. C., Gunn-Moore, F. J., Prystowsky, M. B. & Dholakia, K. 1 Feb 2016 In : Biomedical Optics Express. 7, 2, p. 302-311

    Research output: Research - peer-reviewArticle

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