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Research at St Andrews

Frank J Gunn-Moore

Person

  1. 2018
  2. Published

    1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders

    Benek, O., Hroch, L., Aitken, L., Gunn-Moore, F., Vinklarova, L., Kuca, K., Perez, D. I., Perez, C., Martinez, A., Fisar, Z. & Musilek, K. 2018 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 33, 1, p. 665-670 6 p.

    Research output: Contribution to journalArticle

  3. Published

    All-optical assay to study biological neural networks

    Afshar Saber, W., Gasparoli, F. M., Dirks, M. G., Gunn-Moore, F. J. & Antkowiak, M. 5 Jul 2018 In : Frontiers in Neuroscience. 12, 12 p., 451

    Research output: Contribution to journalArticle

  4. Published

    Alzheimer's disease in humans and other animals: a consequence of postreproductive life span and longevity rather than aging

    Gunn-Moore, D., Kaidanovich-Beilin, O., Gallego Iradi, M. C., Gunn-Moore, F. & Lovestone, S. Feb 2018 In : Alzheimer's and Dementia. 14, 2, p. 195-204

    Research output: Contribution to journalArticle

  5. E-pub ahead of print

    Light sheet fluorescence microscopy for neuroscience

    Corsetti, S., Gunn-Moore, F. & Dholakia, K. 23 Jul 2018 In : Journal of Neuroscience Methods. In press

    Research output: Contribution to journalArticle

  6. Published

    Light-sheet microscopy with attenuation-compensated propagation-invariant beams

    Nylk, J., McCluskey, K. A., Preciado, M., Mazilu, M., Yang, Z., Gunn-Moore, F. J., Aggarwal, S., Tello, J. A., Ferrier, D. E. K. & Dholakia, K. 6 Apr 2018 In : Science Advances. 4, 4, 14 p., eaar4817

    Research output: Contribution to journalArticle

  7. Published

    Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

    Yu, Q., Wang, Y., Yan, S., Origlia, N., Rutigliano, G., Yu, H., Ainge, J. A., Yan, S. F., Gunn-Moore, F. J. & Yan, S. S. 30 Jul 2018 In : Nature Communications. 9, 14 p., 2968

    Research output: Contribution to journalArticle

  8. 2017
  9. Published

    6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation

    Benek, O., Hroch, L., Aitken, L., Dolezal, R., Guest, P., Benkova, M., Soukup, O., Musil, K., Hughes, R., Kuca, K., Smith, T. K., Gunn-Moore, F. & Musilek, K. Jun 2017 In : Medicinal Chemistry. 13, 4, p. 345-358 14 p.

    Research output: Contribution to journalArticle

  10. Published

    In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease

    Aitken, L., Baillie, G., Pannifer, A., Morrison, A., Jones, P. S., Smith, T. K., McElroy, S. P. & Gunn-Moore, F. J. Jul 2017 In : SLAS Discovery. 22, 6, p. 676-685 11 p.

    Research output: Contribution to journalArticle

  11. Published

    Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

    Hroch, L., Guest, P., Benek, O., Soukup, O., Janockova, J., Dolezal, R., Kuca, K., Aitken, L., Smith, T. K., Gunn-Moore, F., Zala, D., Ramsay, R. R. & Musilek, K. 1 Feb 2017 In : Bioorganic & Medicinal Chemistry. 25, 3, p. 1143-1152 10 p.

    Research output: Contribution to journalArticle

  12. 2016
  13. Published

    Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF)

    Kailainathan, S., Piers, T. M., Yi, J. H., Choi, S., Fahey, M. S., Borger, E., Gunn-Moore, F. J., O'Neill, L., Lever, M., Whitcomb, D. J., Cho, K. & Allen, S. J. Feb 2016 In : Pharmacological Research. 104, p. 97-107 11 p.

    Research output: Contribution to journalArticle

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