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Research at St Andrews

Rafael Guimaraes da Silva


  1. 2018
  2. Published

    Catalytic and anticatalytic snapshots of a short-form ATP phosphoribosyltransferase

    Alphey, M. S., Fisher, G., Ge, Y., Gould, E. R., Guerreiro Machado, T. F., Liu, H., Florence, G. J., Naismith, J. H. & da Silva, R. G. 11 May 2018 In : ACS Catalysis. 8, p. 5601-5610 10 p.

    Research output: Research - peer-reviewArticle

  3. Published

    Discovery of trifluoromethyl glycol carbamates as potent and selective covalent monoacylglycerol lipase (MAGL) inhibitors for treatment of neuroinflammation

    McAllister, L. , Butler, C. , Mente, S. , O'Neil, S. V. , Fonseca, K. , Piro, J. , Cianfrogna, J. , Foley, T. , Gilbert, A. , Harris, A. , Helal, C. J. , Johnson, D. S. , Montgomery, J. I. , Nason, D. M. , Noell, S. , Pandit, J. , Rogers, B. N. , Samad, T. A. , Shaffer, C. L. , da Silva, R. G. & 3 others Uccello, D. P., Webb, D. & Brodney, M. A. 12 Apr 2018 In : Journal of Medicinal Chemistry. 61, 7, p. 3008–3026

    Research output: Research - peer-reviewArticle

  4. 2017
  5. Published

    Kinetics and structure of a cold-adapted hetero-octameric ATP phosphoribosyltransferase

    Stroek, R., Ge, Y., Talbot, P. D., Glok, M. K., Bernas, K. E., Thomson, C. M., Gould, E. R., Alphey, M. S., Liu, H., Florence, G. J., Naismith, J. H. & da Silva, R. G. 7 Feb 2017 In : Biochemistry. 56, 5, p. 793-803 11 p.

    Research output: Research - peer-reviewArticle

  6. 2014
  7. Published

    A continuous and direct assay to monitor leucine-rich repeat kinase 2 activity

    Silva, R. G., Geoghegan, K. F., Qiu, X. & Aulabaugh, A. 2014 In : Analytical Biochemistry. 450, 1, p. 63-69

    Research output: Research - peer-reviewArticle

  8. 2013
  9. Published

    Selective mitochondrial staining with small fluorescent probes: importance, design, synthesis, challenges and trends for new markers

    Neto, B. A. D., Correa, J. R. & Silva, R. G. 2013 In : RSC Advances. 3, p. 5291-5301

    Research output: Research - peer-reviewArticle

  10. Published

    The Biginelli reaction with an imidazolium-tagged recyclable iron catalyst: kinetics, mechanism, and antitumoral activity

    Ramos, L. M., Guido, B. C., Nobrega, C. C., Correa, J. R., Silva, R. G., de Oliveira, H. C. B., Gomes, A. F., Gozzo, F. C. & Neto, B. A. D. 2013 In : Chemistry - A European Journal. 19, p. 4156-4168

    Research output: Research - peer-reviewArticle

  11. 2012
  12. Published

    Constrained bonding environment in the Michaelis complex of Trypanosoma cruzi uridine phosphorylase

    Silva, R. G., Kipp, D. R. & Schramm, V. L. 2012 In : Biochemistry. 51, p. 6715-6717

    Research output: Research - peer-reviewArticle

  13. Published

    Synthesis, properties and highly selective mitochondria staining with novel, stable and superior benzothiadiazole fluorescent probes

    Neto, B. A. D., Carvalho, . P. H. P. R., Santos, D. C. B. D., Gatto, C. C., Ramos, L. M., de Vasconcelos, N. M., Correa, J. R., Costa, M. B., de Oliveira, H. C. B. & Silva, R. G. 2012 In : RSC Advances. 2, p. 1524-1532

    Research output: Research - peer-reviewArticle

  14. 2011
  15. Published

    Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase

    Silva, R. G., Hirschi, J. S., Ghanem, M., Murkin, A. S. & Schramm, V. L. 2011 In : Biochemistry. 50, p. 2701-2709

    Research output: Research - peer-reviewArticle

  16. Published
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