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Research at St Andrews

Rafael Guimaraes da Silva

Person

  1. Published

    A continuous and direct assay to monitor leucine-rich repeat kinase 2 activity

    Silva, R. G., Geoghegan, K. F., Qiu, X. & Aulabaugh, A., 2014, In : Analytical Biochemistry. 450, 1, p. 63-69

    Research output: Contribution to journalArticle

  2. Published

    Allosteric activation shifts the rate-limiting step in a short-form ATP phosphoribosyltransferase

    Fisher, G., Thomson, C. M., Stroek, R., Czekster, C. M., Hirschi, J. S. & da Silva, R. G., 24 Jul 2018, In : Biochemistry. 57, 29, p. 4357-4367

    Research output: Contribution to journalArticle

  3. Published

    An exceptionally potent inhibitor of human CD73

    Bowman, C. E., da Silva, R. G., Pham, A. & Young, S. W., 6 Aug 2019, In : Biochemistry. 58, 31, p. 3331-3334 4 p.

    Research output: Contribution to journalArticle

  4. Published

    Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase

    Silva, R. G., Hirschi, J. S., Ghanem, M., Murkin, A. S. & Schramm, V. L., 2011, In : Biochemistry. 50, p. 2701-2709

    Research output: Contribution to journalArticle

  5. Published

    Beta-Ketoacyl-Acyl Carrier Protein (ACP) Reductase: Kinetic and Chemical Mechanisms

    Silva, R. G., de Carvalho, L. P. S., Blanchard, J. S., Santos, D. S. & Basso, L. A., 2006, In : Biochemistry. 45, p. 13064-13073

    Research output: Contribution to journalArticle

  6. Published

    Catalytic and anticatalytic snapshots of a short-form ATP phosphoribosyltransferase

    Alphey, M. S., Fisher, G., Ge, Y., Gould, E. R., Guerreiro Machado, T. F., Liu, H., Florence, G. J., Naismith, J. H. & da Silva, R. G., 11 May 2018, In : ACS Catalysis. 8, 6, p. 5601-5610 10 p.

    Research output: Contribution to journalArticle

  7. Published

    Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase

    Silva, R. G., de Carvalho, LPS., Oliveira, JS., Pinto, CA., Mendes, MA., Palma, MS., Basso, LA. & Santos, DS., 2003, In : Protein Expression and Purification. 27, p. 158-164

    Research output: Contribution to journalArticle

  8. Published

    Constrained bonding environment in the Michaelis complex of Trypanosoma cruzi uridine phosphorylase

    Silva, R. G., Kipp, D. R. & Schramm, V. L., 2012, In : Biochemistry. 51, p. 6715-6717

    Research output: Contribution to journalArticle

  9. Published

    Crystal structure of human PNP complexed with guanine

    de Azevedo, WF., Canduri, F., dos Santos, D., Pereira, J., Dias, MVB., Silva, R. G., Mendes, MA., Basso, LA., Palma, MS. & Santos, DS., 2003, In : Biochemical and Biophysical Research Communications. 312, p. 767-772

    Research output: Contribution to journalArticle

  10. Published

    Crystal structure of human purine nucleoside phosphorylase at 2.3 A resolution

    de Azevedo, WF., Canduri, F., dos Santos, DM., Silva, R. G., Oliveira, JS., de Carvalho, LPS., Basso, LA., Mendes, MA., Palma, MS. & Santos, DS., 2003, In : Biochemical and Biophysical Research Communications. 308, p. 545-552

    Research output: Contribution to journalArticle

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