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Research at St Andrews

Rafael Guimaraes da Silva

Person

  1. 2007
  2. Published

    Purine Nucleoside Phosphorylase: A Potential Target for the Development of Drugs to Treat T-Cell- and Apicomplexan Parasite-Mediated Diseases

    Silva, R. G., Nunes, J. E. S., Canduri, F., Borges, J. C., Gava, L. M., Moreno, F. B., Basso, L. A. & Santos, D. S., 2007, In : Current Drug Targets. 8, p. 413-422

    Research output: Contribution to journalArticle

  3. 2006
  4. Published

    Beta-Ketoacyl-Acyl Carrier Protein (ACP) Reductase: Kinetic and Chemical Mechanisms

    Silva, R. G., de Carvalho, L. P. S., Blanchard, J. S., Santos, D. S. & Basso, L. A., 2006, In : Biochemistry. 45, p. 13064-13073

    Research output: Contribution to journalArticle

  5. Published

    Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: Purification and characterization

    Fonseca, I. O., Magalhaes, M. L. B., Oliveira, J. S., Silva, R. G., Mendes, M. A., Palma, M. S., Santos, D. S. & Basso, L. A., 2006, In : Protein Expression and Purification. 46, p. 429-437

    Research output: Contribution to journalArticle

  6. 2005
  7. Published

    Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine

    Silva, R. G., Pereira, J. H., Canduri, F., de Azevedo, WF., Basso, LA. & Santos, DS., 2005, In : Archives of Biochemistry and Biophysics. 442, p. 49-58

    Research output: Contribution to journalArticle

  8. Published

    Structure of human PNP complexed with ligands

    Canduri, F., Silva, R. G., dos Santos, D. M., Palma, MS., Basso, LA., Santos, DS. & de Azevedo, WF., 2005, In : Acta Crystallographica. Section D, Biological crystallography. 61, p. 856-862

    Research output: Contribution to journalArticle

  9. 2004
  10. Published

    Purine Nucleoside Phosphorylase Activity in Rat Cerebrospinal Fluid

    Silva, R. G., Santos, DS., Basso, LA., Oses, JP., Wofchuk, S., Portela, LVC. & Souza, DO., 2004, In : Neurochemical Research. 29, p. 1831-1835

    Research output: Contribution to journalArticle

  11. Published

    Structures of human purine nucleoside phosphorylase complexed with inosine and ddI

    Canduri, F., dos Santos, DM., Silva, R. G., Mendes, MA., Basso, LA., MS, P., de Azevedo, WF. & Santos, DS., 2004, In : Biochemical and Biophysical Research Communications. 313, p. 907-914

    Research output: Contribution to journalArticle

  12. 2003
  13. Published

    Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase

    Silva, R. G., de Carvalho, LPS., Oliveira, JS., Pinto, CA., Mendes, MA., Palma, MS., Basso, LA. & Santos, DS., 2003, In : Protein Expression and Purification. 27, p. 158-164

    Research output: Contribution to journalArticle

  14. Published

    Crystal structure of human PNP complexed with guanine

    de Azevedo, WF., Canduri, F., dos Santos, D., Pereira, J., Dias, MVB., Silva, R. G., Mendes, MA., Basso, LA., Palma, MS. & Santos, DS., 2003, In : Biochemical and Biophysical Research Communications. 312, p. 767-772

    Research output: Contribution to journalArticle

  15. Published

    Crystal structure of human purine nucleoside phosphorylase at 2.3 A resolution

    de Azevedo, WF., Canduri, F., dos Santos, DM., Silva, R. G., Oliveira, JS., de Carvalho, LPS., Basso, LA., Mendes, MA., Palma, MS. & Santos, DS., 2003, In : Biochemical and Biophysical Research Communications. 308, p. 545-552

    Research output: Contribution to journalArticle

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