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Research at St Andrews

Samantha J. Pitt

Person

  1. Review article › Research › Peer-reviewed
  2. Published

    Exploring the biophysical evidence that mammalian two pore channels are NAADP-activated calcium-permeable channels

    Pitt, S. J., Reilly O'Donnell, B. & Sitsapesan, R., 1 Aug 2016, In : The Journal of Physiology. 594, 15, p. 4171-4179 9 p.

    Research output: Contribution to journalReview article

  3. Published

    Glycosaminoglycan neutralization in coagulation control

    Sobczak, A. I. S., Pitt, S. J. & Stewart, A. J., Jun 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 6, p. 1258-1270 14 p.

    Research output: Contribution to journalReview article

  4. Published

    Influence of zinc on glycosaminoglycan neutralisation during coagulation

    Sobczak, A. I. S., Pitt, S. J. & Stewart, A. J., Sep 2018, In : Metallomics. 10, 9, p. 1180-1190 11 p.

    Research output: Contribution to journalReview article

  5. Abstract › Research › Peer-reviewed
  6. Published

    TPC1 is a proton permeable channel that can be independently activated by cytosolic calcium or NAADP

    Pitt, S. J., Lam, A., Galione, A. & Sitsapesan, R., 28 Jan 2014, In : Biophysical Journal. 106, 2, p. 642A-642A 1 p.

    Research output: Contribution to journalAbstract

  7. Letter › Research › Peer-reviewed
  8. Published

    Response to Qian and Colvin: zinc-mediated regulation of the cardiac ryanodine receptor occurs via multiple binding sites

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 19 Feb 2016, In : Journal of Biological Chemistry. 291, 8, p. 4267

    Research output: Contribution to journalLetter

  9. Article › Research › Peer-reviewed
  10. Published

    17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats

    Zafirovic, S., Obradovic, M., Sudar-Milovanovic, E., Jovanovic, A., Stanimirovic, J., Stewart, A. J., Pitt, S. J. & Isenovic, E. R., 5 May 2017, In : Molecular and Cellular Endocrinology. 446, p. 12-20 9 p.

    Research output: Contribution to journalArticle

  11. Published

    A family of Type VI secretion system effector proteins that form ion-selective pores

    Mariano, G., Trunk, K., Williams, D. J., Monlezun, L., Strah, H., Pitt, S. J. & Coulthurst, S. J., 2 Dec 2019, In : Nature Communications. 10, p. 1-15 15 p., 5484.

    Research output: Contribution to journalArticle

  12. Published

    A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats

    Stanimirovic, J., Obradovic, M., Jovanovic, A., Sudar-Milovanovic, E., Zafirovic, S., Pitt, S. J., Stewart, A. J. & Isenovic, E. R., 1 Apr 2016, In : Nitric Oxide. 54, p. 51-59 9 p.

    Research output: Contribution to journalArticle

  13. Published

    Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

    Kapsalis, C., Wang, B., El Mkami, H., Pitt, S. J., Schnell, J., Smith, T. K., Lippiat, J., Bode, B. E. & Pliotas, C., 10 Oct 2019, In : Nature Communications. 10, 14 p., 4619.

    Research output: Contribution to journalArticle

  14. Published

    Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet

    Jovanovic, A., Obradovic, M., Sudar-Milovanovic, E., Stewart, A. J., Pitt, S. J., Alvantic, D., Aleksic, E. & Isenovic, E. R., Dec 2017, In : Molecular and Cellular Biochemistry. 436, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalArticle

  15. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In : Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticle

  16. Published

    FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6

    Galfre, E., Pitt, S. J., Venturi, E., Sitsapesan, M., Zaccai, N. R., Tsaneva-Atanasova, K., O'Neill, S. & Sitsapesan, R., 21 Feb 2012, In : PLoS ONE. 7, 2, e31956.

    Research output: Contribution to journalArticle

  17. Published

    FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

    Venturi, E., Galfre, E., O'Brien, F., Pitt, S. J., Bellamy, S., Sessions, R. B. & Sitsapesan, R., 18 Feb 2014, In : Biophysical Journal. 106, 4, p. 824-833 10 p.

    Research output: Contribution to journalArticle

  18. Published

    Influence of a high-fat diet on cardiac iNOS in female rats

    Jovanovic, A., Sudar-Milovanovic, E., Obradovic, M., Pitt, S. J., Stewart, A. J., Zafirovic, S., Stanimirovic, J., Radak, D. & Isenovic, E. R., 2017, In : Current Vascular Pharmacology. 15, 5, p. 491-500 10 p.

    Research output: Contribution to journalArticle

  19. Published

    Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 10 Jul 2015, In : Journal of Biological Chemistry. 290, 28, p. 17599-17610 12 p.

    Research output: Contribution to journalArticle

  20. Published

    Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE

    Tamburrino, G., Llabrés, S., Vickery, O., Pitt, S. J. & Zachariae, U., 6 Dec 2017, In : Scientific Reports. 7, 10 p., 17091.

    Research output: Contribution to journalArticle

  21. Published

    TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+

    Pitt, S. J., Funnell, T. M., Sitsapesan, M., Venturi, E., Rietdorf, K., Ruas, M., Ganesan, A., Gosain, R., Churchill, G. C., Zhu, M. X., Parrington, J., Galione, A. & Sitsapesan, R., 5 Nov 2010, In : Journal of Biological Chemistry. 285, 45, p. 35039-35046

    Research output: Contribution to journalArticle

  22. Published

    Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes

    Sobczak, A. I. S., Stefanowicz, F., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2019, In : BioMetals. 32, 1, p. 123-138 16 p.

    Research output: Contribution to journalArticle

  23. Published

    Zinc controls RyR2 activity during excitation-contraction coupling

    Stewart, A. J. & Pitt, S. J., Sep 2015, In : Channels. 9, 5, p. 223-225

    Research output: Contribution to journalArticle

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