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Research at St Andrews

Samantha J. Pitt

Person

  1. Published

    A family of Type VI secretion system effector proteins that form ion-selective pores

    Mariano, G., Trunk, K., Williams, D. J., Monlezun, L., Strah, H., Pitt, S. J. & Coulthurst, S. J., 2 Dec 2019, In : Nature Communications. 10, p. 1-15 15 p., 5484.

    Research output: Contribution to journalArticle

  2. E-pub ahead of print

    Reduced plasma magnesium levels in type-1 diabetes associate with prothrombotic changes in fibrin clotting and fibrinolysis

    Sobczak, A. I. S., Phoenix, F. A., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., 3 Jan 2020, In : Thrombosis and Haemostasis. eFirst, 10 p.

    Research output: Contribution to journalArticle

  3. Published

    Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

    Kapsalis, C., Wang, B., El Mkami, H., Pitt, S. J., Schnell, J., Smith, T. K., Lippiat, J., Bode, B. E. & Pliotas, C., 10 Oct 2019, In : Nature Communications. 10, 14 p., 4619.

    Research output: Contribution to journalArticle

  4. Published

    Plasma non-esterified fatty acids contribute to increased coagulability in type-2 diabetes through altered plasma zinc speciation

    Sobczak, A. I. S., Katundu, K. G. H., Phoenix, F. A., Khazaipoul, S., Yu, R., Lampiao, F., Stefanowicz, F., Blindauer, C. A., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., 28 Aug 2019, In : biorxiv. 38 p.

    Research output: Contribution to journalArticle

  5. Published

    Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes

    Sobczak, A. I. S., Stefanowicz, F., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2019, In : BioMetals. 32, 1, p. 123-138 16 p.

    Research output: Contribution to journalArticle

  6. Published

    Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE

    Tamburrino, G., Llabrés, S., Vickery, O., Pitt, S. J. & Zachariae, U., 6 Dec 2017, In : Scientific Reports. 7, 10 p., 17091.

    Research output: Contribution to journalArticle

  7. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In : Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticle

  8. Published

    Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet

    Jovanovic, A., Obradovic, M., Sudar-Milovanovic, E., Stewart, A. J., Pitt, S. J., Alvantic, D., Aleksic, E. & Isenovic, E. R., Dec 2017, In : Molecular and Cellular Biochemistry. 436, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalArticle

  9. Published

    17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats

    Zafirovic, S., Obradovic, M., Sudar-Milovanovic, E., Jovanovic, A., Stanimirovic, J., Stewart, A. J., Pitt, S. J. & Isenovic, E. R., 5 May 2017, In : Molecular and Cellular Endocrinology. 446, p. 12-20 9 p.

    Research output: Contribution to journalArticle

  10. Published

    Influence of a high-fat diet on cardiac iNOS in female rats

    Jovanovic, A., Sudar-Milovanovic, E., Obradovic, M., Pitt, S. J., Stewart, A. J., Zafirovic, S., Stanimirovic, J., Radak, D. & Isenovic, E. R., 2017, In : Current Vascular Pharmacology. 15, 5, p. 491-500 10 p.

    Research output: Contribution to journalArticle

  11. Published

    A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats

    Stanimirovic, J., Obradovic, M., Jovanovic, A., Sudar-Milovanovic, E., Zafirovic, S., Pitt, S. J., Stewart, A. J. & Isenovic, E. R., 1 Apr 2016, In : Nitric Oxide. 54, p. 51-59 9 p.

    Research output: Contribution to journalArticle

  12. Published

    Zinc controls RyR2 activity during excitation-contraction coupling

    Stewart, A. J. & Pitt, S. J., Sep 2015, In : Channels. 9, 5, p. 223-225

    Research output: Contribution to journalArticle

  13. Published

    Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 10 Jul 2015, In : Journal of Biological Chemistry. 290, 28, p. 17599-17610 12 p.

    Research output: Contribution to journalArticle

  14. Published

    Examining a new role for zinc in regulating calcium release in cardiac muscle

    Pitt, S. J. & Stewart, A. J., 1 Jun 2015, In : Biochemical Society Transactions. 43, 3, p. 359-363

    Research output: Contribution to journalArticle

  15. Published

    Reconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca2+

    Pitt, S. J., Lam, A. K. M., Rietdorf, K., Galione, A. & Sitsapesan, R., 20 May 2014, In : Science Signaling. 7, 326, ra46.

    Research output: Contribution to journalArticle

  16. Published

    In vivo effects of 17β-estradiol on cardiac Na+/K+-ATPase expression and activity in rat heart

    Obradovic, M., Stewart, A. J., Pitt, S. J., Labudovic-Borovic, M., Sudar, E., Petrovic, V., Zafirovic, S., Maravic-Stojkovic, V., Vasic, V. & Isenovic, E. R., 5 May 2014, In : Molecular and Cellular Endocrinology. 388, 1-2, p. 58-68

    Research output: Contribution to journalArticle

  17. Published

    FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

    Venturi, E., Galfre, E., O'Brien, F., Pitt, S. J., Bellamy, S., Sessions, R. B. & Sitsapesan, R., 18 Feb 2014, In : Biophysical Journal. 106, 4, p. 824-833 10 p.

    Research output: Contribution to journalArticle

  18. Published

    TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model

    Venturi, E., Matyjaszkiewicz, A., Pitt, S. J., Tsaneva-Atanasova, K., Nishi, M., Yamazaki, D., Takeshima, H. & Sitsapesan, R., Aug 2013, In : Pflügers Archiv: European Journal of Physiology. 465, 8, p. 1135-1148

    Research output: Contribution to journalArticle

  19. Published

    FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6

    Galfre, E., Pitt, S. J., Venturi, E., Sitsapesan, M., Zaccai, N. R., Tsaneva-Atanasova, K., O'Neill, S. & Sitsapesan, R., 21 Feb 2012, In : PLoS ONE. 7, 2, e31956.

    Research output: Contribution to journalArticle

  20. Published

    From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors?

    Venturi, E., Pitt, S. J., Galfre, E. & Sitsapesan, R., 2012, In : Cardiovascular Therapeutics. 30, 2, p. 109-16

    Research output: Contribution to journalArticle

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