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Research at St Andrews

Samantha J. Pitt

Person

  1. 2003
  2. Published

    Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis.

    Vial, C., Pitt, S. J., Roberts, J. A., Rolf, M. G., Mahaut-Smith, M. P. & Evans, R. J., 2003, In: Blood. 102, 10, p. 3646-51

    Research output: Contribution to journalArticlepeer-review

  3. 2005
  4. Published

    Potentiation of P2Y receptors by physiological elevations of extracellular K+ via a mechanism independent of Ca2+ influx.

    Pitt, S. J., Martinez-Pinna, J., Barnard, E. A. & Mahaut-Smith, M. P., 2005, In: Molecular Pharmacology. 67, 5, p. 1705-13

    Research output: Contribution to journalArticlepeer-review

  5. 2008
  6. Published

    High intracellular chloride slows the decay of glycinergic currents

    Pitt, S. J., Sivilotti, L. G. & Beato, M. B., Nov 2008, In: The Journal of Neuroscience. 28, 45, p. 11454-11467

    Research output: Contribution to journalArticlepeer-review

  7. 2010
  8. Published

    Charade of the SR K+-channel: two ion-channels, TRIC-A and TRIC-B, masquerade as a single K+-channel

    Pitt, S. J., Park, K-H., Nishi, M., Urashima, T., Aoki, S., Yamazaki, D., Ma, J., Takeshima, H. & Sitsapesan, R., 2010, In: Biophysical Journal. 99, 2, p. 417-426

    Research output: Contribution to journalArticlepeer-review

  9. Published

    TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+

    Pitt, S. J., Funnell, T. M., Sitsapesan, M., Venturi, E., Rietdorf, K., Ruas, M., Ganesan, A., Gosain, R., Churchill, G. C., Zhu, M. X., Parrington, J., Galione, A. & Sitsapesan, R., 5 Nov 2010, In: Journal of Biological Chemistry. 285, 45, p. 35039-35046

    Research output: Contribution to journalArticlepeer-review

  10. 2011
  11. Published

    Ca2+-dependent phosphorylation of RyR2 can uncouple channel gating from direct cytosolic Ca2+ regulation

    Carter, S., Pitt, S. J., Colyer, J. & Sitsapesan, R., 2011, In: Journal of Membrane Biology. 240, 1, p. 21-33

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Mitsugumin 23 forms a massive bowl-shaped assembly and cation-conducting channel.

    Venturi, E., Mio, K., Nishi, M., Ogura, T., Moriya, T., Pitt, S. J., Okuda, K., Kakizawa, S., Sitsapesan, R., Sato, C. & Takeshima, H., 2011, In: Biochemistry. 50, 13, p. 2623-32

    Research output: Contribution to journalArticlepeer-review

  13. 2012
  14. Published

    FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6

    Galfre, E., Pitt, S. J., Venturi, E., Sitsapesan, M., Zaccai, N. R., Tsaneva-Atanasova, K., O'Neill, S. & Sitsapesan, R., 21 Feb 2012, In: PLoS ONE. 7, 2, e31956.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors?

    Venturi, E., Pitt, S. J., Galfre, E. & Sitsapesan, R., 2012, In: Cardiovascular Therapeutics. 30, 2, p. 109-16

    Research output: Contribution to journalArticlepeer-review

  16. 2013
  17. Published

    TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model

    Venturi, E., Matyjaszkiewicz, A., Pitt, S. J., Tsaneva-Atanasova, K., Nishi, M., Yamazaki, D., Takeshima, H. & Sitsapesan, R., Aug 2013, In: Pflügers Archiv: European Journal of Physiology. 465, 8, p. 1135-1148

    Research output: Contribution to journalArticlepeer-review

  18. 2014
  19. Published

    In vivo effects of 17β-estradiol on cardiac Na+/K+-ATPase expression and activity in rat heart

    Obradovic, M., Stewart, A. J., Pitt, S. J., Labudovic-Borovic, M., Sudar, E., Petrovic, V., Zafirovic, S., Maravic-Stojkovic, V., Vasic, V. & Isenovic, E. R., 5 May 2014, In: Molecular and Cellular Endocrinology. 388, 1-2, p. 58-68

    Research output: Contribution to journalArticlepeer-review

  20. Published

    FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

    Venturi, E., Galfre, E., O'Brien, F., Pitt, S. J., Bellamy, S., Sessions, R. B. & Sitsapesan, R., 18 Feb 2014, In: Biophysical Journal. 106, 4, p. 824-833 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Reconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca2+

    Pitt, S. J., Lam, A. K. M., Rietdorf, K., Galione, A. & Sitsapesan, R., 20 May 2014, In: Science Signaling. 7, 326, ra46.

    Research output: Contribution to journalArticlepeer-review

  22. 2015
  23. Published

    Examining a new role for zinc in regulating calcium release in cardiac muscle

    Pitt, S. J. & Stewart, A. J., 1 Jun 2015, In: Biochemical Society Transactions. 43, 3, p. 359-363

    Research output: Contribution to journalArticlepeer-review

  24. Published

    Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 10 Jul 2015, In: Journal of Biological Chemistry. 290, 28, p. 17599-17610 12 p.

    Research output: Contribution to journalArticlepeer-review

  25. Published

    Zinc controls RyR2 activity during excitation-contraction coupling

    Stewart, A. J. & Pitt, S. J., Sep 2015, In: Channels. 9, 5, p. 223-225

    Research output: Contribution to journalArticlepeer-review

  26. 2016
  27. Published

    A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats

    Stanimirovic, J., Obradovic, M., Jovanovic, A., Sudar-Milovanovic, E., Zafirovic, S., Pitt, S. J., Stewart, A. J. & Isenovic, E. R., 1 Apr 2016, In: Nitric Oxide. 54, p. 51-59 9 p.

    Research output: Contribution to journalArticlepeer-review

  28. 2017
  29. Published

    17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats

    Zafirovic, S., Obradovic, M., Sudar-Milovanovic, E., Jovanovic, A., Stanimirovic, J., Stewart, A. J., Pitt, S. J. & Isenovic, E. R., 5 May 2017, In: Molecular and Cellular Endocrinology. 446, p. 12-20 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Published

    Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet

    Jovanovic, A., Obradovic, M., Sudar-Milovanovic, E., Stewart, A. J., Pitt, S. J., Alvantic, D., Aleksic, E. & Isenovic, E. R., Dec 2017, In: Molecular and Cellular Biochemistry. 436, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalArticlepeer-review

  31. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In: Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticlepeer-review

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