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Research at St Andrews

Samantha J. Pitt

Person

  1. Article › Research › Peer-reviewed
  2. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In : Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticle

  3. Published

    Examining a new role for zinc in regulating calcium release in cardiac muscle

    Pitt, S. J. & Stewart, A. J., 1 Jun 2015, In : Biochemical Society Transactions. 43, 3, p. 359-363

    Research output: Contribution to journalArticle

  4. Published

    FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6

    Galfre, E., Pitt, S. J., Venturi, E., Sitsapesan, M., Zaccai, N. R., Tsaneva-Atanasova, K., O'Neill, S. & Sitsapesan, R., 21 Feb 2012, In : PLoS ONE. 7, 2, e31956.

    Research output: Contribution to journalArticle

  5. Published

    FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

    Venturi, E., Galfre, E., O'Brien, F., Pitt, S. J., Bellamy, S., Sessions, R. B. & Sitsapesan, R., 18 Feb 2014, In : Biophysical Journal. 106, 4, p. 824-833 10 p.

    Research output: Contribution to journalArticle

  6. Published

    From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors?

    Venturi, E., Pitt, S. J., Galfre, E. & Sitsapesan, R., 2012, In : Cardiovascular Therapeutics. 30, 2, p. 109-16

    Research output: Contribution to journalArticle

  7. Published

    High intracellular chloride slows the decay of glycinergic currents

    Pitt, S. J., Sivilotti, L. G. & Beato, M. B., Nov 2008, In : The Journal of Neuroscience. 28, 45, p. 11454-11467

    Research output: Contribution to journalArticle

  8. Published

    Influence of a high-fat diet on cardiac iNOS in female rats

    Jovanovic, A., Sudar-Milovanovic, E., Obradovic, M., Pitt, S. J., Stewart, A. J., Zafirovic, S., Stanimirovic, J., Radak, D. & Isenovic, E. R., 2017, In : Current Vascular Pharmacology. 15, 5, p. 491-500 10 p.

    Research output: Contribution to journalArticle

  9. Published

    Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 10 Jul 2015, In : Journal of Biological Chemistry. 290, 28, p. 17599-17610 12 p.

    Research output: Contribution to journalArticle

  10. Published

    Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis.

    Vial, C., Pitt, S. J., Roberts, J. A., Rolf, M. G., Mahaut-Smith, M. P. & Evans, R. J., 2003, In : Blood. 102, 10, p. 3646-51

    Research output: Contribution to journalArticle

  11. Published

    Mitsugumin 23 forms a massive bowl-shaped assembly and cation-conducting channel.

    Venturi, E., Mio, K., Nishi, M., Ogura, T., Moriya, T., Pitt, S. J., Okuda, K., Kakizawa, S., Sitsapesan, R., Sato, C. & Takeshima, H., 2011, In : Biochemistry. 50, 13, p. 2623-32

    Research output: Contribution to journalArticle

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