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Research at St Andrews

Samantha J. Pitt

Person

  1. 2021
  2. Published

    Albumin-mediated alteration of plasma zinc speciation by fatty acids modulates blood clotting in type-2 diabetes

    Sobczak, A. I. S., Katundu, K. G. H., Phoenix, F. A., Khazaipoul, S., Yu, R., Lampiao, F., Stefanowicz, F., Blindauer, C. A., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., 21 Mar 2021, In: Chemical Science. 12, 11, p. 4079-4093 15 p.

    Research output: Contribution to journalArticlepeer-review

  3. Published
  4. 2020
  5. Published

    Monitoring contractility in cardiac tissue with cellular resolution using biointegrated microlasers

    Schubert, M., Woolfson, L., Barnard, I. R. M., Dorward, A., Casement, B., Morton, A., Robertson, G. B., Appleton, P. L., Miles, G. B., Tucker, C. S., Pitt, S. J. & Gather, M. C., Jul 2020, In: Nature Photonics. 14, 7, p. 452–458 12 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Reduced plasma magnesium levels in type-1 diabetes associate with prothrombotic changes in fibrin clotting and fibrinolysis

    Sobczak, A. I. S., Phoenix, F. A., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2020, In: Thrombosis and Haemostasis. 120, 2, p. 243-252 10 p.

    Research output: Contribution to journalArticlepeer-review

  7. 2019
  8. Published

    A family of Type VI secretion system effector proteins that form ion-selective pores

    Mariano, G., Trunk, K., Williams, D. J., Monlezun, L., Strah, H., Pitt, S. J. & Coulthurst, S. J., 2 Dec 2019, In: Nature Communications. 10, 15 p., 5484.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

    Kapsalis, C., Wang, B., El Mkami, H., Pitt, S. J., Schnell, J., Smith, T. K., Lippiat, J., Bode, B. E. & Pliotas, C., 10 Oct 2019, In: Nature Communications. 10, 14 p., 4619.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes

    Sobczak, A. I. S., Stefanowicz, F., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2019, In: BioMetals. 32, 1, p. 123-138 16 p.

    Research output: Contribution to journalArticlepeer-review

  11. 2017
  12. Published

    17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats

    Zafirovic, S., Obradovic, M., Sudar-Milovanovic, E., Jovanovic, A., Stanimirovic, J., Stewart, A. J., Pitt, S. J. & Isenovic, E. R., 5 May 2017, In: Molecular and Cellular Endocrinology. 446, p. 12-20 9 p.

    Research output: Contribution to journalArticlepeer-review

  13. Published

    Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet

    Jovanovic, A., Obradovic, M., Sudar-Milovanovic, E., Stewart, A. J., Pitt, S. J., Alvantic, D., Aleksic, E. & Isenovic, E. R., Dec 2017, In: Molecular and Cellular Biochemistry. 436, 1-2, p. 49-58 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Published

    Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage

    Reilly-O'Donnell, B., Robertson, G. B., Karumbi, A., McIntyre, C., Bal, W., Nishi, M., Takeshima, H., Stewart, A. J. & Pitt, S. J., 11 Aug 2017, In: Journal of Biological Chemistry. 292, 32, p. 13361-13373 13 p.

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Influence of a high-fat diet on cardiac iNOS in female rats

    Jovanovic, A., Sudar-Milovanovic, E., Obradovic, M., Pitt, S. J., Stewart, A. J., Zafirovic, S., Stanimirovic, J., Radak, D. & Isenovic, E. R., 2017, In: Current Vascular Pharmacology. 15, 5, p. 491-500 10 p.

    Research output: Contribution to journalArticlepeer-review

  16. Published

    Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE

    Tamburrino, G., Llabrés, S., Vickery, O., Pitt, S. J. & Zachariae, U., 6 Dec 2017, In: Scientific Reports. 7, 10 p., 17091.

    Research output: Contribution to journalArticlepeer-review

  17. 2016
  18. Published

    A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats

    Stanimirovic, J., Obradovic, M., Jovanovic, A., Sudar-Milovanovic, E., Zafirovic, S., Pitt, S. J., Stewart, A. J. & Isenovic, E. R., 1 Apr 2016, In: Nitric Oxide. 54, p. 51-59 9 p.

    Research output: Contribution to journalArticlepeer-review

  19. 2015
  20. Published

    Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release

    Woodier, J., Rainbow, R. D., Stewart, A. J. & Pitt, S. J., 10 Jul 2015, In: Journal of Biological Chemistry. 290, 28, p. 17599-17610 12 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Zinc controls RyR2 activity during excitation-contraction coupling

    Stewart, A. J. & Pitt, S. J., Sep 2015, In: Channels. 9, 5, p. 223-225

    Research output: Contribution to journalArticlepeer-review

  22. 2014
  23. Published

    FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation

    Venturi, E., Galfre, E., O'Brien, F., Pitt, S. J., Bellamy, S., Sessions, R. B. & Sitsapesan, R., 18 Feb 2014, In: Biophysical Journal. 106, 4, p. 824-833 10 p.

    Research output: Contribution to journalArticlepeer-review

  24. 2012
  25. Published

    FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6

    Galfre, E., Pitt, S. J., Venturi, E., Sitsapesan, M., Zaccai, N. R., Tsaneva-Atanasova, K., O'Neill, S. & Sitsapesan, R., 21 Feb 2012, In: PLoS ONE. 7, 2, e31956.

    Research output: Contribution to journalArticlepeer-review

  26. 2010
  27. Published

    TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+

    Pitt, S. J., Funnell, T. M., Sitsapesan, M., Venturi, E., Rietdorf, K., Ruas, M., Ganesan, A., Gosain, R., Churchill, G. C., Zhu, M. X., Parrington, J., Galione, A. & Sitsapesan, R., 5 Nov 2010, In: Journal of Biological Chemistry. 285, 45, p. 35039-35046

    Research output: Contribution to journalArticlepeer-review

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