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Research at St Andrews

Terry K Smith

Person

  1. 2018
  2. Published

    Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease

    Gaspar, L., Coron, R. P., Kongthoo Lin, P., Costa, D. M., Perez-Cabezas, B., Tavares, J., Roura-Ferrer, M., Ramos, I., Ronin, C., Major, L. L., Ciesielski, F., Pemberton, I. K., MacDougall, J., Ciapetti, P., Smith, T. K. & Cordeiro-da-Silva, A. 22 Jan 2018 In : PLoS Neglected Tropical Diseases. 12, 1, 30 p., e0006180

    Research output: Research - peer-reviewArticle

  3. E-pub ahead of print

    Design and synthesis of broad spectrum trypanosomatid selective inhibitors

    Fraser, A. L., Menzies, S. K., King, E. F. B., Tulloch, L., Gould, E. R., Zacharova, M., Smith, T. K. & Florence, G. J. 9 Jan 2018 In : ACS Infectious Diseases. In press

    Research output: Research - peer-reviewArticle

  4. Published

    Direct and indirect approaches to identify drug modes of action

    Tulloch, L. B., Menzies, S. K., Coron, R. P., Roberts, M. D., Florence, G. J. & Smith, T. K. Jan 2018 In : IUBMB Life. 70, 1, p. 9-22

    Research output: Research - peer-reviewReview article

  5. 2017
  6. Published

    Simplifying nature: towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins

    Gould, E. R., King, E. F. B., Menzies, S. K., Fraser, A. L., Tulloch, L. B., Zacharova, M. K., Smith, T. K. & Florence, G. J. 15 Nov 2017 In : Bioorganic & Medicinal Chemistry. 25, 22, p. 6126-6136

    Research output: Research - peer-reviewArticle

  7. Published

    ADIPOSE TISSUE IS A MAJOR RESERVOIR OF FUNCTIONALLY DISTINCT TRYPANOSOMA BRUCEI PARASITES

    Trindade, S., Rijo-Ferreira, F., Carvalho, T., Pinto-Neves, D., Guegan, F., Aresta-Branco, F., Bento, F., Young, S. A., Pinto, A., Van den Abbeele, J., Ribeiro, R. M., Dias, S., Smith, T. K. & Figueiredo, L. M. Nov 2017 In : American Journal of Tropical Medicine and Hygiene. 95, 5, p. 606-606 1 p.

    Research output: Research - peer-reviewAbstract

  8. Published

    ANALOGS OF THE NATURAL PRODUCT CHAMUVARININ TARGET THE TRYPANOSOMATID FOF1-ATP SYNTHASE MITOCHONDRIAL COMPLEX V

    Menzies, S. K., Tulloch, L. B., Fraser, A. L., Gould, E. R., King, E. F., Zacharova, M. K., Florence, G. J. & Smith, T. K. Nov 2017 In : American Journal of Tropical Medicine and Hygiene. 95, 5, p. 164-164 1 p.

    Research output: Research - peer-reviewAbstract

  9. Published

    CHARACTERIZATION OF THE TRYPANOSOMATID SECONDARY ALTERNATIVE OXIDASE - A NOVEL POTENTIAL DRUG TARGET

    Menzies, S. K., Tulloch, L. B., Fraser, A. L., Gould, E. R., King, E. F., Zacharova, M. K., Florence, G. J. & Smith, T. K. Nov 2017 In : American Journal of Tropical Medicine and Hygiene. 95, 5, p. 410-410 1 p.

    Research output: Research - peer-reviewAbstract

  10. Published
  11. Published

    Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues

    Tulloch, L. B., Menzies, S. K., Fraser, A. L., Gould, E. R., King, E. F., Zacharova, M. K., Florence, G. J. & Smith, T. K. 5 Sep 2017 In : PLoS Neglected Tropical Diseases. 11, 9, 28 p., e0005886

    Research output: Research - peer-reviewArticle

  12. Published

    In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease

    Aitken, L., Baillie, G., Pannifer, A., Morrison, A., Jones, P. S., Smith, T. K., McElroy, S. P. & Gunn-Moore, F. J. Jul 2017 In : SLAS Discovery. 22, 6, p. 676-685 11 p.

    Research output: Research - peer-reviewArticle

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