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A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol: direct reductive amination of chiral ketones using hydrogenation catalysts

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A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol : direct reductive amination of chiral ketones using hydrogenation catalysts. / Gilbert, Sophie H.; Viseur, Virginie; Clarke, Matthew L.

In: Chemical Communications, Vol. 55, No. 45, 07.06.2019, p. 6409-6412.

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Gilbert, SH, Viseur, V & Clarke, ML 2019, 'A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol: direct reductive amination of chiral ketones using hydrogenation catalysts', Chemical Communications, vol. 55, no. 45, pp. 6409-6412. https://doi.org/10.1039/c9cc00923j

APA

Gilbert, S. H., Viseur, V., & Clarke, M. L. (2019). A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol: direct reductive amination of chiral ketones using hydrogenation catalysts. Chemical Communications, 55(45), 6409-6412. https://doi.org/10.1039/c9cc00923j

Vancouver

Gilbert SH, Viseur V, Clarke ML. A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol: direct reductive amination of chiral ketones using hydrogenation catalysts. Chemical Communications. 2019 Jun 7;55(45):6409-6412. https://doi.org/10.1039/c9cc00923j

Author

Gilbert, Sophie H. ; Viseur, Virginie ; Clarke, Matthew L. / A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol : direct reductive amination of chiral ketones using hydrogenation catalysts. In: Chemical Communications. 2019 ; Vol. 55, No. 45. pp. 6409-6412.

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@article{7014ad212fc6485bbe12f55512fdd12f,
title = "A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol: direct reductive amination of chiral ketones using hydrogenation catalysts",
abstract = "High diastereoselectivity was observed in the Rh-catalysed reductive amination of 3-arylcyclohexanones to form tertiary amines. This was incorporated into a one-pot enantioselective conjugate addition and diastereoselective reductive amination, including an example of assisted tandem catalysis.",
keywords = "Asymmetric hydrogenation, Reductive amination, Homogeneous catalysis",
author = "Gilbert, {Sophie H.} and Virginie Viseur and Clarke, {Matthew L.}",
note = "Authors thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [PhD studentship to SG; Grant code: EP/L016419/1]. ",
year = "2019",
month = jun,
day = "7",
doi = "10.1039/c9cc00923j",
language = "English",
volume = "55",
pages = "6409--6412",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "45",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - A consecutive process for C–C and C–N bond formation with high enantio-and diastereocontrol

T2 - direct reductive amination of chiral ketones using hydrogenation catalysts

AU - Gilbert, Sophie H.

AU - Viseur, Virginie

AU - Clarke, Matthew L.

N1 - Authors thank the University of St Andrews, and the EPSRC Centre for Doctoral Training in Critical Resource Catalysis (CRITICAT) for financial support [PhD studentship to SG; Grant code: EP/L016419/1].

PY - 2019/6/7

Y1 - 2019/6/7

N2 - High diastereoselectivity was observed in the Rh-catalysed reductive amination of 3-arylcyclohexanones to form tertiary amines. This was incorporated into a one-pot enantioselective conjugate addition and diastereoselective reductive amination, including an example of assisted tandem catalysis.

AB - High diastereoselectivity was observed in the Rh-catalysed reductive amination of 3-arylcyclohexanones to form tertiary amines. This was incorporated into a one-pot enantioselective conjugate addition and diastereoselective reductive amination, including an example of assisted tandem catalysis.

KW - Asymmetric hydrogenation

KW - Reductive amination

KW - Homogeneous catalysis

U2 - 10.1039/c9cc00923j

DO - 10.1039/c9cc00923j

M3 - Article

VL - 55

SP - 6409

EP - 6412

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 45

ER -

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