Skip to content

Research at St Andrews

A controlled pilot trial of a nurse-led intervention (Mini-AFTERc) to manage fear of cancer recurrence in patients affected by breast cancer

Research output: Contribution to journalArticle

Abstract

Background: Fear of cancer recurrence (FCR) is common in people affected by breast cancer. FCR is associated with increased health service and medication use, anxiety, depression and reduced quality of life. Existing interventions for FCR are time and resource intensive, making implementation in a National Health Service (NHS) setting challenging. To effectively manage FCR in current clinical practice, less intensive FCR interventions are required. Mini-AFTERc is a structured 30-min counselling intervention delivered over the telephone and is designed to normalise moderate FCR levels by targeting unhelpful behaviours and misconceptions about cancer recurrence.

This multi-centre non-randomised controlled pilot trial will investigate the feasibility of delivering the Mini-AFTERc intervention, its acceptability and usefulness, in relation to specialist breast cancer nurses (SBCNs) and patients. This protocol describes the rationale, methods and analysis plan for this pilot trial of the Mini-AFTERc intervention in everyday practice.

Methods: This study will run in four breast cancer centres in NHS Scotland, two intervention and two control centres. SBCNs at intervention centres will be trained to deliver the Mini-AFTERc intervention. Female patients who have completed primary breast cancer treatment in the previous 6 months will be screened for moderate FCR (FCR4 score: 10‑14). Participants at intervention centres will receive the Mini-AFTERc intervention within 2 weeks of recruitment. SBCNs will audio record the intervention telephone discussions with participants. Fidelity of intervention implementation will be assessed from audio recordings. All participants will complete three separate follow-up questionnaires assessing changes in FCR, anxiety, depression and quality of life over 3 months. Normalisation process theory (NPT) will form the framework for semi-structured interviews with 20% of patients and all SBCNs. Interviews will explore participants’ experience of the study, acceptability and usefulness of the intervention and factors influencing implementation within clinical practice. The ADePT process will be adopted to systematically problem solve and refine the trial design.

Discussion: Findings will provide evidence for the potential effectiveness, fidelity, acceptability and practicality of the Mini-AFTERc intervention, and will inform the design and development of a large randomised controlled trial (RCT).
Close

Details

Original languageEnglish
Article number60
Number of pages10
JournalPilot and Feasibility Studies
Volume6
DOIs
Publication statusPublished - 7 May 2020

    Research areas

  • Breast cancer, Psychological, Fear of cancer recurrence, Feasibility, Brief intervention

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. MapMySmoke–a context aware mobile phone application targeted at smoking cessation

    Schick, R. S., Humphris, G. M., Kelsey, T. W., Marston, J. & Sampson, K., 22 Nov 2016.

    Research output: Contribution to conferencePoster

  2. Adult dental anxiety: recent assessment approaches and psychological management in a dental practice setting

    Humphris, G. M., Spyt, J., Herbison, A. & Kelsey, T., May 2016, In : Dental Update. 43, 4, p. 388-394 7 p.

    Research output: Contribution to journalArticle

  3. Screening for fear of cancer recurrence: instrument validation and current status in early stage lung cancer patients

    Lee, Y-H., Hu, C-C., Humphris, G., Huang, I-C., You, K-L., Jhang, S-Y., Chen, J-S. & Lai, Y-H., Jun 2020, In : Journal of the Formosan Medical Association. 119, 6, p. 1101-1108

    Research output: Contribution to journalArticle

Related by journal

  1. A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting

    Yuan, S., Humphris, G., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In : Pilot and Feasibility Studies. 4, 9 p., 136.

    Research output: Contribution to journalArticle

  2. Design and development of a complex narrative intervention delivered by text messages to reduce binge drinking among socially disadvantaged men

    Irvine, L., Melson, A. J., Williams, B., Sniehotta, F. F., Humphris, G. & Crombie, I. K., 6 Jun 2018, In : Pilot and Feasibility Studies. 4, 11 p., 105.

    Research output: Contribution to journalArticle

  3. Physical activity referral to cardiac rehabilitation, leisure centre or telephone-delivered consultations in post-surgical people with breast cancer: a mixed methods process evaluation

    Hubbard, G., Campbell, A., Fisher, A., Harvie, M., Maltinsky, W., Mullen, R., Banks, E., Gracey, J., Gorely, T., Munro, J. & Ozakinci, G., 1 Jun 2018, In : Pilot and Feasibility Studies. 4, 14 p., 108.

    Research output: Contribution to journalArticle

ID: 267650311

Top