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A highly active manganese catalyst for enantioselective ketone and ester hydrogenation

Research output: Research - peer-reviewArticle



Magnus B. Widegren, Gavin J. Harkness, Alexandra M. Z. Slawin, David B. Cordes, Matthew L. Clarke

School/Research organisations


A new hydrogenation catalyst based on a manganese complex of a chiral P,N,N ligand has been found to be especially active for the hydrogenation of esters down to 0.1 mol% catalyst loading, and gives up to 97% e.e. in the hydrogenation of pro-chiral deactivated ketones at 30-50 oC.


Original languageEnglish
Pages (from-to)5919-5922
Number of pages4
JournalAngewandte Chemie
Issue number21
Early online date20 Apr 2017
StatePublished - 15 May 2017

    Research areas

  • Manganese, Reduction, Ester hydrogenation, Ferrocene, Enantioselective catalysis

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  1. Angewandte Chemie (Journal)

    Woollins, J. D. (Editor)
    2005 → …

    Activity: Publication peer-review and editorial workEditor of research journal

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