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A highly active manganese catalyst for enantioselective ketone and ester hydrogenation

Research output: Contribution to journalArticlepeer-review

Author(s)

Magnus B. Widegren, Gavin J. Harkness, Alexandra M. Z. Slawin, David B. Cordes, Matthew L. Clarke

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Abstract

A new hydrogenation catalyst based on a manganese complex of a chiral P,N,N ligand has been found to be especially active for the hydrogenation of esters down to 0.1 mol% catalyst loading, and gives up to 97% e.e. in the hydrogenation of pro-chiral deactivated ketones at 30-50 oC.
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Details

Original languageEnglish
Pages (from-to)5919-5922
Number of pages4
JournalAngewandte Chemie
Volume129
Issue number21
Early online date20 Apr 2017
DOIs
Publication statusPublished - 15 May 2017

    Research areas

  • Manganese, Reduction, Ester hydrogenation, Ferrocene, Enantioselective catalysis

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