Skip to content

Research at St Andrews

A highly active manganese catalyst for enantioselective ketone and ester hydrogenation

Research output: Contribution to journalArticle

Author(s)

Magnus B. Widegren, Gavin J. Harkness, Alexandra M. Z. Slawin, David B. Cordes, Matthew L. Clarke

School/Research organisations

Abstract

A new hydrogenation catalyst based on a manganese complex of a chiral P,N,N ligand has been found to be especially active for the hydrogenation of esters down to 0.1 mol% catalyst loading, and gives up to 97% e.e. in the hydrogenation of pro-chiral deactivated ketones at 30-50 oC.
Close

Details

Original languageEnglish
Pages (from-to)5919-5922
Number of pages4
JournalAngewandte Chemie
Volume129
Issue number21
Early online date20 Apr 2017
DOIs
Publication statusPublished - 15 May 2017

    Research areas

  • Manganese, Reduction, Ester hydrogenation, Ferrocene, Enantioselective catalysis

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. STA-27, a porous Lewis acidic scandium MOF with an unexpected topology type prepared with 2,3,5,6-tetrakis(4-carboxyphenyl)pyrazine

    Prasad, R., Seidner, S., Cordes, D. B., Lozinska, M., Dawson, D., Thompson, M., Düren, T., Chakarova, K., Mihaylov, M., Hadjiivanov, K., Hoffmann, F., Slawin, A. M. Z., Ashbrook, S. E., Clarke, M. & Wright, P., 14 Mar 2019, In : Journal of Materials Chemistry. 7, 10, p. 5685-5701

    Research output: Contribution to journalArticle

  2. A highly active manganese catalyst for enantioselective ketone and ester hydrogenation

    Widegren, M. B., Harkness, G. J., Slawin, A. M. Z., Cordes, D. B. & Clarke, M. L., 8 May 2017, In : Angewandte Chemie International Edition. 56, 21, p. 5825-5828 4 p.

    Research output: Contribution to journalArticle

  3. On the functional group tolerance of ester hydrogenation and polyester depolymerisation catalysed by ruthenium complexes of tridentate aminophosphine ligands

    Fuentes García, J. A., Smith, S., Scharbert, M. T., Carpenter, I., Cordes, D. B., Slawin, A. M. Z. & Clarke, M., 20 Jul 2015, In : Chemistry - A European Journal. 21, 30, p. 10851–10860

    Research output: Contribution to journalArticle

Related by journal

  1. Angewandte Chemie (Journal)

    J Derek Woollins (Editor)
    2005 → …

    Activity: Publication peer-review and editorial work typesEditor of research journal

Related by journal

  1. Sub-micromolar pulse dipolar EPR spectroscopy reveals increasing CuII-labelling of double-histidine motifs with lower temperature

    Wort, J., Ackermann, K., Giannoulis, A., Stewart, A. J., Norman, D. & Bode, B. E., 19 Aug 2019, In : Angewandte Chemie. 131, 34, p. 11807-11811 6 p.

    Research output: Contribution to journalArticle

  2. Aryloxide-facilitated catalyst turnover in enantioselective α,β-unsaturated acyl ammonium catalysis

    Matviitsuk, A., Greenhalgh, M., Barrios Antunez, D., Slawin, A. & Smith, A. D., 25 Sep 2017, In : Angewandte Chemie. 129, 40, p. 12450-12455 6 p.

    Research output: Contribution to journalArticle

  3. Enzyme activity by design: an artificial rhodium hydroformylase for linear aldehydes

    Jarvis, A., Obrecht, L., Deuss, P., Laan, W., Gibson, E. K., Wells, P. P. & Kamer, P. C. J., 23 Oct 2017, In : Angewandte Chemie. 129, 44, p. 13784-13788

    Research output: Contribution to journalArticle

  4. Expansion of the ADOR strategy for the synthesis of new zeolites: the synthesis of IPC-12 from zeolite UOV

    Kasneryk, V., Shamzhy, M., Opanasenko, M., Wheatley, P. S., Morris, S. A., Russell, S. E., Mayoral, A., Trachta, M., Čejka, J. & Morris, R. E., 3 Apr 2017, In : Angewandte Chemie. 56, 15, p. 4324-4327 5 p.

    Research output: Contribution to journalArticle

ID: 249586929

Top