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A one-pot synthesis of symmetrical and unsymmetrical dipeptide ureas

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Abstract

We describe a flexible and high yielding synthesis of 1,3-disubstituted ureas, that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C labelled ureas, from amino acids and carbon dioxide at atmospheric pressure.

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Original languageEnglish
Pages (from-to)5603-5609
Number of pages8
JournalEuropean Journal of Organic Chemistry
Volume25
Early online date30 Jul 2015
DOIs
StatePublished - Sep 2015

    Research areas

  • Peptides, Dipeptide, Urea, Isotopic labelling

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