Skip to content

Research at St Andrews

Application of one-pot three-component condensation reaction for the synthesis of new organophosphorus-sulfur macrocycles

Research output: Contribution to journalArticlepeer-review

Author(s)

School/Research organisations

Abstract

An efficient approach has been developed for the synthesis of new phosphorus–sulfur heterocycles by a one-pot three-component condensation reaction of a four-membered-ring thionation reagent [Lawesson’s reagent or its ferrocene analogue (2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide)], an alkane- or arenedithiol, and a dihaloalkane at room temperature in the presence of triethylamine. The simple synthesis method with mild conditions (room temperature and normal reactant concentrations) enhances further the application of the multicomponent reaction in the preparation of novel phosphorus–sulfur heterocycles. Six representative X-ray structures confirmed the formation of these macrocycles.
Close

Details

Original languageEnglish
JournalSynlett
VolumeeFirst
Early online date19 Apr 2018
DOIs
Publication statusE-pub ahead of print - 19 Apr 2018

    Research areas

  • Multicomponent reactions, Macrocycles, Phosphorus-sulfur heterocycles, Lawesson's reagent, Dithiols, Dihaloalkanes

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Bridging (thionylimido)metal complexes

    McGeachie, L. J. R., Buehl, M., Cordes, D. B., Slawin, A. M. Z. & Woollins, J. D., 27 May 2021, In: Inorganic Chemistry. Articles ASAP, 5 p.

    Research output: Contribution to journalArticlepeer-review

  2. Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

    Hua, G., Carpenter-Warren, C. L., Cordes, D. B., Slawin, A. M. Z. & Woollins, J. D., 19 Apr 2021, In: Molecules. 26, 8, 10 p., 2367.

    Research output: Contribution to journalArticlepeer-review

  3. Organo phosphorus-sulfur-nitrogen heterocycles from thionation of Schiff bases

    Hua, G., Cordes, D. B., Slawin, A. M. Z. & Woollins, J. D., 24 Feb 2021, In: Zeitschrift für Anorganische und Allgemeine Chemie. 647, 4, p. 239-244 7 p.

    Research output: Contribution to journalArticlepeer-review

  4. Thionylimido complexes

    McGeachie, L. J. R., Carpenter-Warren, C. L., Cordes, D. B., Buehl, M., Gray, S. J., Hua, G., Slawin, A. M. Z. & Woollins, J. D., 27 Nov 2020, In: Zeitschrift für Anorganische und Allgemeine Chemie. 646, 22, p. 1795-1798 5 p.

    Research output: Contribution to journalArticlepeer-review

  5. Novel five- and six-membered ring phosphorus-selenium heterocycles from selenation of amido-Schiff bases

    Hua, G., Cordes, D. B., Slawin, A. M. Z. & Woollins, J. D., 26 May 2020, In: ACS Omega. 5, 20, p. 11737-11744 8 p.

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. The problem with problems: fundamental to applied research using palladium

    Watson, A. J. B., 5 May 2020, In: Synlett. 31

    Research output: Contribution to journalArticlepeer-review

  2. A cascade Suzuki-Miyaura/Diels-Alder protocol: exploring the bifunctional utility of vinyl Bpin

    Cain, D. L., McLaughlin, C., Molloy, J., Carpenter-Warren, C., Anderson, N. A. & Watson, A. J. B., Apr 2019, In: Synlett. 30, 7, p. 787-791 5 p.

    Research output: Contribution to journalArticlepeer-review

  3. Isothiourea-catalysed sequential kinetic resolution of acyclic (±)-1,2-diols

    Harrer, S., Greenhalgh, M. D., Neyyappadath, R. M. & Smith, A. D., Aug 2019, In: Synlett. 30, 13, p. 1555-1560

    Research output: Contribution to journalArticlepeer-review

  4. Dimethylisosorbide (DMI) as a bio-derived solvent for Pd-catalyzed cross-coupling reactions

    Wilson, K. L., Murray, J., Sneddon, H., Jamieson, C. & Watson, A. J. B., Oct 2018, In: Synlett. 29, 17, p. 2293-2297 5 p.

    Research output: Contribution to journalArticlepeer-review

ID: 252589097

Top