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Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae

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Janine T. Bossé, Yanwen Li, Tom G. Atherton, Stephanie Walker, Susanna M. Williamson, Jon Rogers, Roy R. Chaudhuri, Lucy A. Weinert, Matthew T. G. Holden, Duncan J. Maskell, Alexander W. Tucker, Brendan W. Wren, Andrew N. Rycroft, Paul R. Langford, on behalf of BraDP1T consortium

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Abstract

The complete nucleotide sequence of a 7.7kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally.
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Original languageEnglish
Pages (from-to)279-82
Number of pages4
JournalVeterinary Microbiology
Volume178
Issue number3-4
Early online date22 Jul 2015
DOIs
StatePublished - 5 Aug 2015

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