Skip to content

Research at St Andrews

Cognitive consequences of opioid use

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter intends to review the literature that focused around understanding better the neurocognitive impairments in populations with a history of opioid dependence. Most of the data reviewed are designed as cross-sectional studies and therefore do not allow determination whether neurocognitive impairment observed precede drug use, or, if they occur as a consequence of the effects of continued opioid use. A growing line of evidence from human studies highlight that illicit heroin use, methadone and buprenorphine treatment but not chronic use of other opioids present with variable neurocognitive impairments when compared with healthy non-substance using control groups.


Original languageEnglish
Title of host publicationCognition and Addiction: A Researcher’s Guide from Mechanisms towards Interventions
EditorsAntonio Verdejo-Garcia
Number of pages35
Publication statusPublished - 21 Mar 2019

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Effects of opioid dependence on visuospatial memory and its associations with depression and anxiety

    Tolomeo, S., Davey, F., Steele, J. D. & Baldacchino, A. M., 18 Sep 2019, (Accepted/In press) In : Frontiers in Psychiatry.

    Research output: Contribution to journalArticle

  2. Chronic tobacco smoking and neuropsychological impairments: a systematic review and meta-analysis

    Conti, A. A., McLean, L., Tolomeo, S., Steele, D. & Baldacchino, A. M., Jan 2019, In : Neuroscience and Biobehavioral Reviews. 96, p. 143-154 12 p.

    Research output: Contribution to journalReview article

  3. Is (poly-) substance use associated with impaired inhibitory control? A mega-analysis controlling for confounders

    Liu, Y., van den Wildenberg, W. P. M., de Graaf, Y., Ames, S. L., Baldacchino, A., Bø, R., Cadaveira, F., Campanella, S., Christiansen, P., Claus, E. D., Colzato, L. S., Filbey, F. M., Foxe, J. J., Garavan, H., Hendershot, C. S., Hester, R., Jester, J. M., Karoly, H. C., Kräplin, A., Kreusch, F. & 35 othersLandrø, N. I., Littel, M., Steins-Löber, S., London, E. D., López-Caneda, E., Lubman, D. I., Luijten, M., Marczinski, C. A., Metrik, J., Montgomery, C., Papachristou, H., Park, S. M., Paz, A. L., Petit, G., Prisciandaro, J. J., Quednow, B. B., Ray, L. A., Roberts, C. A., Roberts, G. M. P., de Ruiter, M. B., Rupp, C. I., Steele, V. R., Sun, D., Takagi, M., Tapert, S. F., van Holst, R. J., Verdejo-Garcia, A., Vonmoos, M., Wojnar, M., Yao, Y., Yücel, M., Zack, M., Zucker, R. A., Huizenga, H. M. & Wiers, R. W., 15 Jul 2019, In : Neuroscience and Biobehavioral Reviews. 105, p. 288-304

    Research output: Contribution to journalArticle

  4. Craving in opioid use disorder: from neurobiology to clinical practice

    Kakko, J., Alho, H., Baldacchino, A. M., Molina, R., Nava, F. A. & Shaya, G., 30 Aug 2019, In : Frontiers in Psychiatry. 10, 12 p., 592.

    Research output: Contribution to journalReview article

  5. Profiles of visuospatial memory dysfunction in opioid exposed and dependent populations

    Baldacchino, A., Tolomeo, S., Balfour, D. & Matthews, K., May 2019, In : Psychological Medicine. 49, 7, p. 1174-1184 27 p.

    Research output: Contribution to journalArticle

ID: 259001119