Skip to content

Research at St Andrews

Comparative Analysis of Photoluminescence and Upconversion Emission from Individual Carbon Nanotubes for Bioimaging Applications

Research output: Contribution to journalArticlepeer-review


Noemie Danne, Antoine G. Godin, Zhenghong Gao, Juan A. Varela, Laurent Groc, Brahim Lounis, Laurent Cognet

School/Research organisations


Luminescent single-walled carbon nanotubes (SWCNTs) are unique nanoemitters that allow near-infrared single-molecule detection within biological tissues. Interestingly, the recent discovery of upconversion luminescence from (6,5) SWCNTs provides a novel opportunity for deep tissue single SWCNT detection. Yet, the optimal excitation strategy for video-iate imaging of individual SWCNTs within live tissues needs to be determined taking into account the constraints imposed by the biological matter. Here, we directly compare the luminescence efficiencies of single (6,5) SWCNTs excited by continuous-wave lasers at their second-order excitonic transition, at their K-momentum exciton phonon sideband, or through upconversion. For these three excitations spanning visible to near-infrared wavelengths, the relevance of single SWCNT imaging is considered inside brain tissue. The effects of tissue scattering, absorption, autofluorescence, and temperature increase induced by excitation light are systematically examined.



Original languageEnglish
Pages (from-to)359-364
Number of pages11
JournalACS Photonics
Issue number2
Publication statusPublished - 21 Feb 2018

    Research areas

  • single-walled carbon nanotube, photoluminescence, upconversion, single-molecule imaging, bioimaging, NEAR-INFRARED FLUORESCENCE, MICROSCOPY, BRAIN, TRACKING, TISSUE

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. ThX-a next-generation probe for the early detection of amyloid aggregates

    Needham, L. M., Weber, J., Varela, J. A., Fyfe, J. W. B., Do, D. T., Xu, C. K., Tutton, L., Cliffe, R., Keenlyside, B., Klenerman, D., Dobson, C. M., Hunter, C. A., Müller, K. H., O'Holleran, K., Bohndiek, S. E., Snaddon, T. N. & Lee, S. F., 14 May 2020, In: Chemical Science. 11, 18, p. 4578-4583 6 p.

    Research output: Contribution to journalArticlepeer-review

  2. Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

    De, S., Wirthensohn, D. C., Flagmeier, P., Hughes, C., Aprile, F. A., Ruggeri, F. S., Whiten, D. R., Emin, D., Xia, Z., Varela, J. A., Sormanni, P., Kundel, F., Knowles, T. P. J., Dobson, C. M., Bryant, C., Vendruscolo, M. & Klenerman, D., 4 Apr 2019, In: Nature Communications. 10, 11 p., 1541.

    Research output: Contribution to journalArticlepeer-review

  3. Optical structural analysis of individual α-synuclein oligomers

    Varela, J. A., Rodrigues, M., De, S., Flagmeier, P., Gandhi, S., Dobson, C. M., Klenerman, D. & Lee, S. F., 23 Apr 2018, In: Angewandte Chemie International Edition. 57, 18, p. 4886-4890 5 p.

    Research output: Contribution to journalArticlepeer-review

  4. FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions

    Qamar, S., Wang, G., Randle, S. J., Ruggeri, F. S., Varela, J. A., Lin, J. Q., Phillips, E. C., Miyashita, A., Williams, D., Ströhl, F., Meadows, W., Ferry, R., Dardov, V. J., Tartaglia, G. G., Farrer, L. A., Kaminski Schierle, G. S., Kaminski, C. F., Holt, C. E., Fraser, P. E., Schmitt-Ulms, G. & 4 others, Klenerman, D., Knowles, T., Vendruscolo, M. & St George-Hyslop, P., 19 Apr 2018, In: Cell. 173, 3, p. 720-734 e15.

    Research output: Contribution to journalArticlepeer-review

  5. Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain

    Godin, A. G., Varela, J. A., Gao, Z., Danné, N., Dupuis, J. P., Lounis, B., Groc, L. & Cognet, L., Mar 2017, In: Nature Nanotechnology. 12, 3, p. 238-243 6 p.

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. Multiphoton graph states from a solid-state single-photon source

    Li, J-P., Qin, J., Chen, A., Duan, Z-C., Yu, Y., Huo, Y., Hoefling, S., Lu, C-Y., Chen, K. & Pan, J-W., 15 Jul 2020, In: ACS Photonics. 7, 7, p. 1603-1610 8 p.

    Research output: Contribution to journalArticlepeer-review

  2. An efficient quantum photonic phase shift in a low Q-factor regime

    Androvitsaneas, P., Young, A., Lennon, J., Schneider, C., Maier, S., Hinchliff, J., Atkinson, G., Harbord, E., Kamp, M., Höfling, S., Rarity, J. G. & Oulton, R., 20 Feb 2019, In: ACS Photonics. 6, 2, p. 429-435

    Research output: Contribution to journalArticlepeer-review

  3. Coherence and interaction in confined room-temperature polariton condensates with Frenkel excitons

    Betzold, S., Dusel, M., Kyriienko, O., Dietrich, C. P., Klembt, S., Ohmer, J., Fischer, U., Shelykh, I. A., Schneider, C. & Höfling, S., 17 Dec 2019, In: ACS Photonics. Just Accepted

    Research output: Contribution to journalArticlepeer-review

  4. Exact states and spectra of vibrationally dressed polaritons

    Zeb, M. A., Kirton, P. G. & Keeling, J. M. J., 17 Jan 2018, In: ACS Photonics. 5, 1, p. 249-257

    Research output: Contribution to journalArticlepeer-review

ID: 268109603