Skip to content

Research at St Andrews

Evolution of the Hox gene cluster.

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Abstract

The Hox genes are a family of developmental control genes containing a homeobox motif, and tend to be organised in distinctive clustered arrays in animals. Organisation within the cluster can relate to how the genes function. Whilst much has been discovered about the Hox gene cluster in traditional model systems of developmental biology, increasing amounts of data from a wider variety of species are illuminating more about the nature of the Hox cluster deep in animal ancestry, as well as revealing the evolutionary flexibility and derivations along present-day lineages. The consensus view of the Hox cluster is that it patterns the anterior–posterior axis of bilaterally symmetrical (bilaterian) animals and exhibits the phenomenon of colinearity. There is, however, much evolutionary change within this system. This diversity in the Hox system is linked to the evolution of animal diver- sity and informs our understanding of the pre-bilaterian origins of the Hox genes themselves.
Close

Details

Original languageEnglish
Title of host publicationeLS
Place of PublicationChichester
PublisherJohn Wiley and Sons
DOIs
StatePublished - Aug 2012

    Research areas

  • homeobox, bilaterian, cnidarian, Hox gene, Hox cluster

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Two more Posterior Hox genes and Hox cluster dispersal in echinoderms

    Szabó, R. & Ferrier, D. E. K. 27 Dec 2018 In : BMC Evolutionary Biology. 18, 13 p., 203

    Research output: Contribution to journalArticle

  2. Transcriptional regulation of the Ciona Gsx gene in the neural plate

    Hudson, C., Esposito, R., Palladino, A., Staiano, L., Ferrier, D., Faure, E., Lemaire, P., Yasuo, H. & Spagnuolo, A. 21 Dec 2018 In : Developmental Biology. In press

    Research output: Contribution to journalArticle

  3. Amphioxus functional genomics and the origins of vertebrate gene regulation

    Marletaz, F. , Firbas, P. , Maeso, I. , Tena, J. , Bogdanovic, O. , Perry, M. , Wyatt, C. , de la Calle-Mustienes, E. , Bertrand, S. , Burguera, D. , Acemel, R. , van Heeringen, S. , Naranjo, S. , Herrera-Ubeda, C. , Skvortsova, K. , Jimenez-Gancedo, S. , Aldea, D. , Marquez, Y. , Buono, L. , Kozmikova, I. & 41 others Permanyer, J., Louis, A., Albuixech-Crespo, B., Le Petillon, Y., Leon Florian, A., Subirana, L., Balwierz, P. J., Duckett, P., Farahani, E., Aury, J. M., Mangenot, S., Wincker, P., Albalat, R., Benito-Gutierrez, E., Canestro, C., Castro, F., D'Aniello, S., Ferrier, D. E. K., Huang, S., Laudet, V., Marais, G., Pontarotti, P., Schubert, M., Seitz, H., Somorjai, I. M. L., Takahashi, T., Mirabeau, O., Xu, A., Yu, J-K., Carninci, P., Martinez-Morales, J., Crollius, H., Kozmik, Z., Weirauch, M., Garcia-Fernandez, J., Lister, R., Lenhard, B., Holland, P., Escriva, H., Gomez-Skarmeta, J. L. & Irimia, M. 21 Nov 2018 In : Nature. 564, 7734, p. 64-70 29 p.

    Research output: Contribution to journalArticle

  4. Horizons in evolutionary genomics: an interview with David Ferrier

    Ferrier, D. E. K. 1 Nov 2018 In : BMC Biology. 16, 3 p., 124

    Research output: Contribution to journalArticle

  5. Genome biology: unconventional DNA repair in an extreme genome

    Ferrier, D. E. K. & Sogabe, S. 22 Oct 2018 In : Current Biology. 28, 20, p. R1208-R1210

    Research output: Contribution to journalReview article

ID: 26471379