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Experimental models of cryptococcosis

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Author(s)

Wilber Sabiiti, Robin C May, E Rhiannon Pursall

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Abstract

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.
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Original languageEnglish
Article number626745
JournalInternational Journal of Microbiology
Volume2012
DOIs
Publication statusPublished - 2012

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