Skip to content

Research at St Andrews

Exploring the role of phosphorus substituents on the enantioselectivity of Ru-catalysed ketone hydrogenation using tridentate phosphine-diamine ligands

Research output: Contribution to journalArticlepeer-review

DOI

Author(s)

Scott David Phillips, Kristian H. O. Andersson, Nina Kann, Michael T. Kuntz, Marcia B. France, Piotr Wawrzyniak, Matt Clarke

School/Research organisations

Abstract

Methods to produce a range of new phosphine-diamine ligands from phosphino-aldehydes have been developed and a hypothesis that larger P-substituents would increase the enantioselectivity towards the (S) isomer in Ru-catalysed ketone hydrogenation of acetophenone has been examined; the successful validation of this hypothesis is further evidence that the mechanism of these catalysts involves a secondary amine assisted reduction.

Close

Details

Original languageEnglish
Pages (from-to)1336-1339
Number of pages4
JournalCatalysis Science & Technology
Volume1
Issue number8
DOIs
Publication statusPublished - Nov 2011

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Understanding catalyst structure-selectivity relationships in Pd-catalyzed enantioselective methoxycarbonylation of styrene

    Gallarati, S., Dingwall, P., Fuentes García, J. A., Buehl, M. & Clarke, M. L., 14 Dec 2020, In: Organometallics. Articles ASAP, 13 p.

    Research output: Contribution to journalArticlepeer-review

  2. Rhodium catalysts derived from a fluorinated phanephos ligand are highly active catalysts for direct asymmetric reductive amination of secondary amines

    Gilbert, S. H., Tin, S., Fuentes, J. A., Fanjul, T. & Clarke, M. L., 10 Dec 2020, In: Tetrahedron. In Press, 131863.

    Research output: Contribution to journalArticlepeer-review

  3. Manganese-catalysed transfer hydrogenation of esters

    Oates, C., Widegren, M. B. & Clarke, M., 7 Aug 2020, In: Chemical Communications. 56, 61, p. 8635-8638

    Research output: Contribution to journalArticlepeer-review

  4. Phospholane-phosphite ligands for Rh catalyzed enantioselective conjugate addition: unusually reactive catalysts for challenging couplings

    Gilbert, S. H., Fuentes, J. A., Cordes, D. B., Slawin, A. M. Z. & Clarke, M. L., 25 May 2020, In: European Journal of Organic Chemistry. 2020, 20, p. 3071-3076

    Research output: Contribution to journalArticlepeer-review

  5. Towards practical earth abundant reduction catalysis: design of improved catalysts for manganese catalysed hydrogenation

    Widegren, M. B. & Clarke, M. L., 7 Nov 2019, In: Catalysis Science & Technology. 9, 21, p. 6047-6058

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. Ligand electronic fine-tuning and its repercussion on the photocatalytic activity and mechanistic pathways of the copper-photocatalysed aza-Henry Reaction

    Li, C., Dickson, R., Rockstroh, N., Rabeah, J., Cordes, D. B., Slawin, A. M. Z., Hünemörder, P., Spannenberg, A., Buehl, M., Mejía, E., Zysman-Colman, E. & Kamer, P. C. J., 18 Sep 2020, In: Catalysis Science & Technology. Advance Article, 12 p.

    Research output: Contribution to journalArticlepeer-review

  2. Effect of oxygen coordination environment of Ca-Mn oxides on catalytic performance of Pd supported catalysts for aerobic oxidation of 5-hydroxymethyl-2-furfural

    Yang, J., Yu, H., Wang, Y., Qi, F., Liu, H., Lou, L-L., Yu, K., Zhou, W. & Liu, S., 7 Dec 2019, In: Catalysis Science & Technology. 9, 23, p. 6659-6668

    Research output: Contribution to journalArticlepeer-review

  3. Photoredox catalysts based on Earth-abundant metal complexes

    Hockin, B., Li, C., Robertson, N. & Zysman-Colman, E., 21 Feb 2019, In: Catalysis Science & Technology. 9, 4, p. 889-915

    Research output: Contribution to journalArticlepeer-review

  4. Towards practical earth abundant reduction catalysis: design of improved catalysts for manganese catalysed hydrogenation

    Widegren, M. B. & Clarke, M. L., 7 Nov 2019, In: Catalysis Science & Technology. 9, 21, p. 6047-6058

    Research output: Contribution to journalArticlepeer-review

  5. Less hindered ligands give improved catalysts for the nickel catalysed Grignard cross-coupling of aromatic ethers

    Harkness, G. J. & Clarke, M. L., 7 Jan 2018, In: Catalysis Science & Technology. 8, 1, p. 328-334

    Research output: Contribution to journalArticlepeer-review

ID: 17581814

Top