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Genome sequence of the pea aphid Acyrthosiphon pisum

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Genome sequence of the pea aphid Acyrthosiphon pisum. / Ferrier, David Ellard Keith; The International Aphid Genomics Consortium.

In: PLoS Biology, Vol. 8, No. 2, e1000313, 02.2010.

Research output: Contribution to journalArticle

Harvard

Ferrier, DEK & The International Aphid Genomics Consortium 2010, 'Genome sequence of the pea aphid Acyrthosiphon pisum' PLoS Biology, vol. 8, no. 2, e1000313. https://doi.org/doi:10.1371/journal.pbio.1000313

APA

Ferrier, D. E. K., & The International Aphid Genomics Consortium (2010). Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology, 8(2), [e1000313]. https://doi.org/doi:10.1371/journal.pbio.1000313

Vancouver

Ferrier DEK, The International Aphid Genomics Consortium. Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology. 2010 Feb;8(2). e1000313. https://doi.org/doi:10.1371/journal.pbio.1000313

Author

Ferrier, David Ellard Keith ; The International Aphid Genomics Consortium. / Genome sequence of the pea aphid Acyrthosiphon pisum. In: PLoS Biology. 2010 ; Vol. 8, No. 2.

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@article{adaa61efccda47c1b88bf8083f8807af,
title = "Genome sequence of the pea aphid Acyrthosiphon pisum",
abstract = "Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.",
keywords = "Pea aphid, Genome sequence",
author = "Ferrier, {David Ellard Keith} and {The International Aphid Genomics Consortium}",
year = "2010",
month = "2",
doi = "doi:10.1371/journal.pbio.1000313",
language = "English",
volume = "8",
journal = "PLoS Biology",
issn = "1544-9173",
publisher = "Public Library of Science",
number = "2",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Genome sequence of the pea aphid Acyrthosiphon pisum

AU - Ferrier, David Ellard Keith

AU - The International Aphid Genomics Consortium

PY - 2010/2

Y1 - 2010/2

N2 - Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.

AB - Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.

KW - Pea aphid

KW - Genome sequence

U2 - doi:10.1371/journal.pbio.1000313

DO - doi:10.1371/journal.pbio.1000313

M3 - Article

VL - 8

JO - PLoS Biology

T2 - PLoS Biology

JF - PLoS Biology

SN - 1544-9173

IS - 2

M1 - e1000313

ER -

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ID: 2384396