Skip to content

Research at St Andrews

Geographic variation in baseline innate immune function does not follow variation in aridity along a tropical environmental gradient

Research output: Contribution to journalArticlepeer-review

Abstract

Geographic variation in aridity determines environmental productivity patterns, including large-scale variability in pathogens, vectors and associated diseases. If disease risk decreases with increasing aridity and is matched by immune defense, we predict a decrease in innate immune function along a gradient of increasing aridity from the cool-wet forest to the hot-dry Sahel, from south to north in Nigeria. We sampled blood and measured five innate immune indices from 286 Common Bulbuls Pycnonotus barbatus between 6 and 13°N. We sampled in the dry season; we resampled the first location (Jos) also as the last sample location to test temporal change in immune function. Immune indices did not decrease with aridity. One immune index, nitric oxide concentration showed a weak quadratic pattern. In Jos, ovotransferrin concentration, haemagglutination and haemolysis titres increased 12 weeks into the dry season, contrary to expectations that immune indices should decrease with increased dryness. In this tropical system, innate immune function does not decrease with increasing aridity but temporal factors within a location may influence immune function more strongly than spatial variation in aridity, suggesting that immune variation does not follow a simple environmental productivity pattern. Consequently, caution should probably be exercised in predicting effects of climate variability on immune function or disease risk.
Close

Details

Original languageEnglish
Article number5909
Number of pages13
JournalScientific Reports
Volume10
DOIs
Publication statusPublished - 3 Apr 2020

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Duet codes do not enhance neighbour recognition in two closely related species of duetting neotropical wrens

    Quiros Guerrero, E., Rivera-Cáceres, K., Janeiro Silva, M. J., Cresswell, W. & Templeton, C. N., 27 Jan 2021, In: Journal of Avian Biology. Early View

    Research output: Contribution to journalArticlepeer-review

  2. Training future generations to deliver evidence-based conservation and ecosystem management

    Downey, H., Amano, T., Cadotte, M., Cook, C. N., Cooke, S. J., Haddaway, N. R., Jones, J. P. G., Littlewood, N., Walsh, J. C., Abrahams, M. I., Adum, G., Akasaka, M., Alves, J. A., Antwis, R. E., Arellano, E. C., Axmacher, J., Barclay, H., Batty, L., Benítez-López, A., Bennett, J. R. & 98 others, Berg, M. J., Bertolino, S., Biggs, D., Bolam, F. C., Bray, T., Brook, B. W., Bull, J. W., Burivalova, Z., Cabeza, M., Chauvenet, A. L. M., Christie, A. P., Cole, L., Cotton, A. J., Cotton, S., Cousins, S. A. O., Craven, D., Cresswell, W., Cusack, J. J., Dalrymple, S. E., Davies, Z. G., Diaz, A., Dodd, J. A., Felton, A., Fleishman, E., Gardner, C. J., Garside, R., Ghoddousi, A., Gilroy, J. J., Gill, D. A., Gill, J. A., Glew, L., Grainger, M. J., Grass, A. A., Greshon, S., Gundry, J., Hart, T., Hopkins, C. R., Howe, C., Johnson, A., Jones, K. W., Jordan, N. R., Kadoya, T., Kerhoas, D., Koricheva, J., Lee, T. M., Lengyel, S., Livingstone, S. W., Lyons, A., McCabe, G., Millett, J., Strevens, C. M., Moolna, A., Mossman, H. L., Mukherjee, N., Muñoz-Sáez, A., Negrões, N., Norfolk, O., Osawa, T., Papworth, S., Park, K. J., Pellet, J., Phillott, A. D., Plotnik, J. M., Priatna, D., Ramos, A. G., Randall, N., Richards, R. M., Ritchie, E. G., Roberts, D. L., Rocha, R., Rodríguez, J. P., Sanderson, R., Sasaki, T., Savilaakso, S., Sayer, C., Sekercioglu, C., Senzaki, M., Smith, G., Smith, R. J., Soga, M., Soulsbury, C. D., Steer, M. D., Stewart, G., Strange, E. F., Suggitt, A. J., Thompson, R. R. J., Thompson, S., Thornhill, I., Trevelyan, R. J., Usieta, H. O., Venter, O., Webber, A. D., White, R. L., Whittingham, M. J., Wilby, A., Yarnell, R. W., Zamora, V. & Sutherland, W. J., 25 Jan 2021, In: Ecological Solutions and Evidence. 2, 1, 11 p., e12032.

    Research output: Contribution to journalArticlepeer-review

  3. Conservation research output in sub-Saharan Africa is increasing, but only in a few countries

    Pototsky, C. & Cresswell, W., 2 Dec 2020, In: Oryx. 54, FirstView, 10 p.

    Research output: Contribution to journalArticlepeer-review

  4. Movements of Cyprus Wheatear Oenanthe cypriaca fledglings: evidence of a post-fledging home range away from the natal site prior to first migration

    Styles, P., Patchett, R. B., Robins King, J. & Cresswell, W., 25 Nov 2020, In: Journal of Ornithology. First Online, 10 p.

    Research output: Contribution to journalArticlepeer-review

  5. Regional wind patterns likely shape a seasonal migration detour

    Patchett, R. & Cresswell, W., 20 Nov 2020, In: Journal of Avian Biology. 51, 11, 6 p., e02466.

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. Scientific Reports (Journal)

    Matt Carter (Reviewer)

    2020

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  2. Scientific Reports (Journal)

    Manon Karin Schweinfurth (Member of editorial board)

    1 Aug 2019 → …

    Activity: Publication peer-review and editorial work typesEditor of research journal

  3. Scientific Reports (Journal)

    Alan J. Stewart (Member of editorial board)

    Jun 2019 → …

    Activity: Publication peer-review and editorial work typesEditor of research journal

  4. Scientific Reports (Journal)

    Matt Carter (Reviewer)

    2019

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  5. Scientific Reports (Journal)

    Monica Arso Civil (Reviewer)

    Jul 2018 → …

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Related by journal

  1. An open access dataset for developing automated detectors of Antarctic baleen whale sounds and performance evaluation of two commonly used detectors

    Miller, B. S., The IWC-SORP/SOOS Acoustic Trends Working Group, Balcazar, N., Nieukirk, S., Leroy, E. C., Aulich, M., Shabangu, F. W., Dziak, R. P., Lee, W. S., Hong, J. K. & Harris, D., 12 Jan 2021, In: Scientific Reports. 11, 18 p., 806.

    Research output: Contribution to journalArticlepeer-review

  2. Avoiding gauge ambiguities in cavity quantum electrodynamics

    Rouse, D. M., Lovett, B. W., Gauger, E. M. & Westerberg, N., 19 Feb 2021, In: Scientific Reports. 11, 10 p., 4281.

    Research output: Contribution to journalArticlepeer-review

  3. Bayesian Network Analysis reveals resilience of the jellyfish Aurelia aurita to an Irish Sea regime shift

    Mitchell, E. G., Wallace, M. I., Smith, V. A., Wiesenthal, A. A. & Brierley, A. S., 12 Feb 2021, In: Scientific Reports. 11, 1, 14 p., 3707.

    Research output: Contribution to journalArticlepeer-review

  4. Drivers and constraints on offshore foraging in harbour seals

    Vance, H. M., Hooker, S. K., Mikkelsen, L., van Neer, A., Teilmann, J., Siebert, U. & Johnson, M., 22 Mar 2021, In: Scientific Reports. 11, 14 p., 6514.

    Research output: Contribution to journalArticlepeer-review

  5. Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment

    Muiño, E., Maisterra, O., Jiménez-Balado, J., Cullell, N., Carrera, C., Torres-Aguila, N. P., Cárcel-Márquez, J., Gallego-Fabrega, C., Lledós, M., González-Sánchez, J., Olmos-Alpiste, F., Espejo, E., March, Á., Pujol, R., Rodríguez-Campello, A., Romeral, G., Krupinski, J., Martí-Fàbregas, J., Montaner, J., Roquer, J. & 1 others, Fernández-Cadenas, I., 25 Mar 2021, In: Scientific Reports. 11, 12 p., 6846.

    Research output: Contribution to journalArticlepeer-review

ID: 266933003

Top