Skip to content

Research at St Andrews

Green laser light (532nm) activates a chloride current in the C1 neuron of Helix aspersa

Research output: Contribution to journalArticlepeer-review


Five hundred and thirty-two nanometers laser light evokes neuron-specific electrical responses in identified neurons of Helix ganglia. Such responses are intensity-dependent over the range 25-1500 mW, readily reversible and repeatable. Detailed experiments on the C1 neuron, which is inhibited by 532nm light, showed that inhibition results from a selective increase in transmembrane Cl- ion conductance. Experiments with calcium-sensitive microelectrodes suggest that the response does not result from an increase in I Ca2+](i). The change in Cl- ion conductance probably occurs in the extensive plasmalemma infoldings of the proximal axon. (C) 2008 Elsevier Ireland Ltd. All rights reserved.



Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalNeuroscience Letters
Issue number3
Publication statusPublished - 15 Mar 2008

    Research areas

  • chloride currents, laser light, Helix neurones, STIMULATION, CHANNELS, APLYSIA, CALCIUM, CELLS

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Initiating revolutions for optical manipulation: the origins and applications of rotational dynamics of trapped particles

    Bruce, G. D., Rodriguez Sevilla, P. & Dholakia, K., 2021, In: Advances in Physics: X. 6, 1, 74 p., 1838322.

    Research output: Contribution to journalReview articlepeer-review

  2. Incorporation of nitrogen in diamond films – a new way of tuning parameters for optical passive elements

    Kosowska, M., Pawłowska, S., Sankaran, K. J., Majchrowicz, D., Haenen, K., Dholakia, K. & Szczerska, M., 11 Dec 2020, In: Diamond and Related Materials. In Press, 10822.

    Research output: Contribution to journalArticlepeer-review

  3. Extended Kalman filtering projection method to reduce the 3σ noise value of optical biosensors

    Li, K., Gupta, R., Drayton, A., Barth, I., Conteduca, D., Reardon, C., Dholakia, K. & Krauss, T. F., 25 Nov 2020, In: ACS Sensors. 5, 11, p. 3474–3482 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. Microscale diamond protection for a ZnO coated fiber optic sensor

    Kosowska, M., Listewnik, P., Majchrowicz, D., Rycewicz, M., Bechelany, M., Fleger, Y., Chen, M., Fixler, D., Dholakia, K. & Szczerska, M., 5 Nov 2020, In: Scientific Reports. 10, 8 p., 19141.

    Research output: Contribution to journalArticlepeer-review

  5. A new laser technique designed to authenticate rare whisky could also detect disease

    Bruce, G. D. & Dholakia, K., 30 Oct 2020, The Conversation.

    Research output: Contribution to specialist publicationArticle

Related by journal

  1. Oxytocin Receptor (OXTR) does not play a major role in the Aetiology of Autism: Genetic and Molecular Studies

    Tansey, KE., Brookes, KJ., Hill, MJ., Cochrane, LE., Gill, M., Skuse, D., Correia, C., Vincente, A., Kent, L., Gallagher, L. & Anney, RJ., 3 May 2010, In: Neuroscience Letters. 474, 3, p. 163-167

    Research output: Contribution to journalArticlepeer-review

  2. Investigation of Van Gogh-like 2 mRNA Regulation and Localisation in Response to Nonciception in the Brain of Adult Common Carp (Cyprinus carpio)

    Reilly, SC., Kipar, A., Hughes, D. J., Quinn, JP., Cossins, AR. & Sneddon, LU., 2009, In: Neuroscience Letters. 465, 3, p. 290-294

    Research output: Contribution to journalArticlepeer-review

  3. Replication of an Association of a Promoter Polymorphism of the Dopamine Transporter Gene and Attention Deficit Hyperactivity Disorder

    Doyle, C., Brookes, K., Simpson, J., Park, J., Scott, S., Coghill, D., Hawi, Z., Kirley, A., Gill, M. & Kent, L., 22 Sep 2009, In: Neuroscience Letters. 462, 2, p. 179-181 3 p.

    Research output: Contribution to journalArticlepeer-review

  4. Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro

    Oldreive, C. E., Harvey, J. Z. & Doherty, G. H., 13 Jun 2008, In: Neuroscience Letters. 438, 1, p. 17-21 5 p.

    Research output: Contribution to journalArticlepeer-review

ID: 408405