Skip to content

Research at St Andrews

Identification of products from canthaxanthin oxidation

Research output: Research - peer-reviewArticle


Open Access permissions



Raphael C. Mordi, John Christopher Walton

School/Research organisations


Canthaxanthin is a carotenoid that lacks pro-vitamin A activity but is known to have antioxidant activity. The products of its oxidation in oxygen were found to be mainly substituted apo-carotenals and apo-carotenones. The product profile resembles that obtained in the oxidation of β-carotene, except that with canthaxanthin these products are the 4-oxo-β-apo-carotenals and 4-oxo-β-apo-carotenones. Epoxides and diepoxides were clearly identified from β-carotene oxidation but in contrast, with canthaxanthin, apart from 5,6-epoxy-canthaxanthin, which was detected at the early stage of oxidation and minor quantities of 5,6-epoxy-β-ionone and 5,6-epoxy-4-oxo-β-apo-11-carotenal, no other epoxides were detected. The identities of these products lead us to suggest that the mechanism of canthaxanthin oxidation bears significant similarity to that of β-carotene.


Original languageEnglish
Pages (from-to)836-840
Number of pages5
JournalFood Chemistry
Issue numberPart A
Early online date12 Nov 2015
StatePublished - 15 Apr 2016

    Research areas

  • Canthaxanthin, β-Carotene, Carotenoids, Oxidation, Antioxidant, Apo-Carotenoids

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Microhydration and the enhanced acidity of free radicals

    Walton, J. C. 14 Feb 2018 In : Molecules. 23, 2, 423

    Research output: Research - peer-reviewArticle

  2. Enhanced proton loss from neutral free radicals: toward carbon-centered superacids

    Walton, J. C. 8 Feb 2018 In : Journal of Physical Chemistry A. 122, 5, p. 1422-1431 10 p.

    Research output: Research - peer-reviewArticle

  3. Dealkanative main group couplings across the peri-gap

    Taylor, L. J., Buehl, M., Chalmers, B. A., Ray, M. J., Wawrzyniak, P., Walton, J. C., Cordes, D. B., Slawin, A. M. Z., Woollins, J. D. & Kilian, P. 27 Dec 2017 In : Journal of the American Chemical Society. 139, 51, p. 18545-18551

    Research output: Research - peer-reviewArticle

  4. Generation and structure of unique boriranyl radicals

    Walton, J. C., McFadden, T. R. & Curran, D. P. 22 Nov 2017 In : Journal of the American Chemical Society. 139, 46, p. 16514-16517

    Research output: Research - peer-reviewArticle

  5. N- to C-sulfonyl photoisomerisation of dihydropyridinones: a synthetic and mechanistic study

    Yeh, P-P., Taylor, J. E., Stark, D. G., Daniels, D. S. B., Fallan, C., Walton, J. C. & Smith, A. D. 16 Oct 2017 In : Organic & Biomolecular Chemistry. In press

    Research output: Research - peer-reviewArticle

Related by journal

  1. Structural elucidation of olive pomace fed sea bass (Dicentrarchus labrax) polar lipids with cardioprotective activities

    Nasopoulou, C., Smith, T., Detopoulou, M., Tsikrika, C., Papaharisis, L., Barkas, D. & Zabetakis, I. 15 Feb 2014 In : Food Chemistry. 145, p. 1097-1105 9 p.

    Research output: Research - peer-reviewArticle

  2. Hemocyanin-derived phenoloxidase activity: A contributing factor to hyperpigmentation in Nephrops norvegicus

    Coates, C. J. & Nairn, J. 15 Sep 2013 In : Food Chemistry. 140, 1-2, p. 361-369 9 p.

    Research output: Research - peer-reviewArticle

ID: 230675566