Skip to content

Research at St Andrews

Impact of the Diabetes Canada Guideline Dissemination Strategy on the prescription of vascular protective medications: a retrospective cohort study, 2010-2015

Research output: Contribution to journalArticle

DOI

Open Access permissions

Open

Author(s)

Alanna V Rigobon, Sumeet Kalia, Jennica Nichols, Babak Aliarzadeh, Michelle Greiver, Rahim Moineddin, Frank Sullivan, Catherine Yu

School/Research organisations

Abstract

OBJECTIVE: The 2013 Diabetes Canada guidelines launched targeted dissemination tools and a simple assessment for vascular protection. We aimed to 1) examine changes associated with the launch of the 2013 guidelines and additional dissemination efforts in the rates of vascular protective medications prescribed in primary care for older patients with diabetes and 2) examine differences in the rates of prescriptions of vascular protective medications by patient and provider characteristics.

RESEARCH DESIGN AND METHODS: The study population included patients (≥40 years of age) from the Canadian Primary Care Sentinel Surveillance Network with type 2 diabetes and at least one clinic visit from April 2010 to December 2015. An interrupted time series analysis was used to assess the proportion of eligible patients prescribed a statin, ACE inhibitor (ACEI)/angiotensin receptor blocker (ARB), or antiplatelet prescription in each quarter. Proton pump inhibitor (PPI) prescriptions were the reference control.

RESULTS: A dynamic cohort was used where participants were enrolled each quarter using a prespecified set of conditions (range 25,985-70,693 per quarter). There were no significant changes in statin (P = 0.43), ACEI/ARB (P = 0.42), antiplatelet (P = 0.39), or PPI (P = 0.16) prescriptions at baseline (guideline intervention). After guideline publication, there was a significant change in slope for statin (-0.52% per quarter, SE 0.15, P < 0.05), ACEI/ARB (-0.38% per quarter, SE 0.13, P < 0.05) and reference PPI (-0.18% per quarter, SE 0.05, P < 0.05) prescriptions.

CONCLUSIONS: There was a decrease in prescribing trends over time that was not specific to vascular protective medications. More effective knowledge translation strategies are needed to improve vascular protection in diabetes in order for patients to receive the most effective interventions.

Close

Details

Original languageEnglish
Article numberdc180935
JournalDiabetes Care
VolumeEarly
Early online date2 Nov 2018
DOIs
Publication statusE-pub ahead of print - 2 Nov 2018

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Do statins have an effect on depressive symptoms? A systematic review and meta-analysis

    Yatham, M. S., Yatham, K. S., Ravindran, A. V. & Sullivan, F., 1 Oct 2019, In : Journal of Affective Disorders. 257, p. 55-63 9 p.

    Research output: Contribution to journalArticle

  2. Unconditional and conditional monetary incentives to increase response to mailed questionnaires: a randomized controlled study within a trial (SWAT)

    Young, B., Bedford, L., das Nair, R., Gallant, S., Littleford, R., Robertson, J. F. R., Schembri, S., Sullivan, F. M., Vedhara, K., Kendrick, D. & ECLS study team, 22 Jul 2019, In : Journal of Evaluation in Clinical Practice. Early View

    Research output: Contribution to journalArticle

  3. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

    RESTART Collaboration & Sullivan, F., 29 Jun 2019, In : Lancet. 393, 10191, p. 2613-2623 11 p.

    Research output: Contribution to journalArticle

  4. The impact of treatment adherence for patients with diabetes and hypertension on cardiovascular disease risk: a protocol for a retrospective cohort study, 2008-2018

    Su, M., Haldane, V., Upshur, R., Sullivan, F., Garda, F. L. A., Greiver, M. & Wei, X., 31 May 2019, In : JMIR Research Protocols. 8, 5, 11 p., e13571.

    Research output: Contribution to journalArticle

  5. Factors associated with recruitment to randomised controlled trials in general practice: protocol for a systematic review

    Moffat, K. R., Cannon, P., Shi, W. & Sullivan, F., 10 May 2019, In : Trials. 20, 4 p., 66.

    Research output: Contribution to journalArticle

Related by journal

  1. Geographical variation in diabetes prevalence and detection in China: multilevel spatial analysis of 98,058 Adults

    Zhou, M., Astell-Burt, T., Bi, Y., Feng, X., Jiang, Y., Li, Y., Page, A., Wang, L., Xu, Y., Wang, L., Zhao, W. & Ning, G., Jan 2015, In : Diabetes Care. 38, 1, p. 72-81 10 p.

    Research output: Contribution to journalArticle

  2. Is neighbourhood green space associated with a lower risk of Type 2 Diabetes Mellitus? Evidence from 267,072 Australians

    Astell-Burt, T. E., Feng, X. & Kolt, G. S., 2014, In : Diabetes Care. 37, 1, p. 197-201

    Research output: Contribution to journalArticle

  3. Screening Uptake in a Well-Established Diabetic Retinopathy Screening Program The role of geographical access and deprivation

    Leese, G. P., Boyle, P., Feng, Z., Emslie-Smith, A. & Ellis, J. D., Nov 2008, In : Diabetes Care. 31, 11, p. 2131-2135 5 p.

    Research output: Contribution to journalArticle

ID: 256486116

Top