Influence of zinc on glycosaminoglycan neutralisation during coagulation

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Zinc-dependant heparin neutralisation: Charecterisation of zinc-dependant heparin neutralisation by fibrinogen and histidine-rich glycoprotein.
Stewart, A. J. & Pitt, S. J.
27/10/15 → 26/10/18
Project: Studentship
RSE/CRF Samantha Pitt Resrch Fellowship: Molecular mechanisms of NAADP-regulated signalling via Two Pore Channels
Pitt, S. J.
The Royal Society of Edinburgh
1/10/13 → 30/09/18
Project: Fellowship
Role of zinc in controlling histidine: Role of zinc in controlling histidine-rich glycoprotein complex formation: Implications for the development of thrombotic complications.
Stewart, A. J., Naismith, J. & Pitt, S. J.
8/06/15 → 7/06/18
Project: Standard

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Fellowship (1)
Studentship (1)

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Albumin-mediated alteration of plasma zinc speciation by fatty acids modulates blood clotting in type-2 diabetes
Sobczak, A. I. S., Katundu, K. G. H., Phoenix, F. A., Khazaipoul, S., Yu, R., Lampiao, F., Stefanowicz, F., Blindauer, C. A., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., 1 Feb 2021, In: Chemical Science. Advance Article, 15 p.
Research output: Contribution to journal › Article › peer-review
Lipidomic profiling of plasma free fatty acids in type-1 diabetes highlights specific changes in lipid metabolism
Sobczak, A. I. S., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., Jan 2021, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1866, 1, 9 p., 158823.
Research output: Contribution to journal › Article › peer-review
Reduced plasma magnesium levels in type-1 diabetes associate with prothrombotic changes in fibrin clotting and fibrinolysis
Sobczak, A. I. S., Phoenix, F. A., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2020, In: Thrombosis and Haemostasis. 120, 2, p. 243-252 10 p.
Research output: Contribution to journal › Article › peer-review
Plasma non-esterified fatty acids contribute to increased coagulability in type-2 diabetes through altered plasma zinc speciation
Sobczak, A. I. S., Katundu, K. G. H., Phoenix, F. A., Khazaipoul, S., Yu, R., Lampiao, F., Stefanowicz, F., Blindauer, C. A., Pitt, S. J., Smith, T. K., Ajjan, R. A. & Stewart, A. J., 28 Aug 2019, In: biorxiv. 2019, 38 p.
Research output: Contribution to journal › Article
Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes
Sobczak, A. I. S., Stefanowicz, F., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., Feb 2019, In: BioMetals. 32, 1, p. 123-138 16 p.
Research output: Contribution to journal › Article › peer-review

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A metalloproteomic analysis of interactions between plasma proteins and zinc: elevated fatty acid levels affect zinc distribution
Coverdale, J. P. C., Barnett, J. P., Adamu, A. H., Griffiths, E. J., Stewart, A. J. & Blindauer, C. A., 1 Nov 2019, In: Metallomics. 11, 11, p. 1805-1819 15 p.
Research output: Contribution to journal › Article › peer-review