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Manganese catalysed hydrogenation of carbamates and urea-derivatives

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Author(s)

Uttam Das, Amit Kumar, Yehoshoa Ben-David, Mark Iron, David Milstein

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Abstract

We report the hydrogenation of carbamates and urea derivatives, two of the most challenging carbonyl compounds to be hydrogenated, catalyzed for the first time by a complex of an earth-abundant metal. The hydrogenation reaction of these CO2-derived compounds, catalyzed by a manganese pincer complex, yields methanol in addition to amine and alcohol, which makes this methodology a sustainable alternative route for the conversion of CO2 to methanol, involving a base-metal catalyst. Moreover, the hydrogenation proceeds under mild pressure (20 bar). Our observations support a hydrogenation mechanism involving the Mn–H complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments.
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Details

Original languageEnglish
Pages (from-to)12962-12966
JournalJournal of the American Chemical Society
Volume141
Issue number33
Early online date31 Jul 2019
DOIs
Publication statusPublished - 21 Aug 2019

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