Skip to content

Research at St Andrews

Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution

Research output: Contribution to journalReview article

DOI

Open Access permissions

Open

Abstract

Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire genomes. With the ever-increasing amounts of gene and genome sequence data that are becoming available, our understanding of the extent of duplication is greatly improving, both in terms of the scales of duplication events as well as their rates of occurrence. An accurate understanding of these processes is vital if we are to properly understand important events in evolution as well as mechanisms operating at the level of genome organisation. Here we will focus on duplication in animal genomes and how the duplicated sequences are distributed, with the aim of maintaining a focus on principles of evolution and organisation that are most directly applicable to the shaping of our own genome.
Close

Details

Original languageEnglish
Article number846421
JournalInternational Journal of Evolutionary Biology
Volume2012
DOIs
Publication statusPublished - 2012

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Transcriptional regulation of the Ciona Gsx gene in the neural plate

    Hudson, C., Esposito, R., Palladino, A., Staiano, L., Ferrier, D., Faure, E., Lemaire, P., Yasuo, H. & Spagnuolo, A., 15 Apr 2019, In : Developmental Biology. 448, 2, p. 88-100 13 p.

    Research output: Contribution to journalArticle

  2. Space and time in Hox/ParaHox gene cluster evolution.

    Ferrier, D. E. K., 2019, Perspectives on Evolutionary Developmental Biology: Essays for Alessandro Minelli. Fusco, G. (ed.). Padova: Padova University Press, p. 245-258

    Research output: Chapter in Book/Report/Conference proceedingChapter

  3. Two more Posterior Hox genes and Hox cluster dispersal in echinoderms

    Szabó, R. & Ferrier, D. E. K., 27 Dec 2018, In : BMC Evolutionary Biology. 18, 13 p., 203.

    Research output: Contribution to journalArticle

  4. Amphioxus functional genomics and the origins of vertebrate gene regulation

    Marletaz, F., Firbas, P., Maeso, I., Tena, J., Bogdanovic, O., Perry, M., Wyatt, C., de la Calle-Mustienes, E., Bertrand, S., Burguera, D., Acemel, R., van Heeringen, S., Naranjo, S., Herrera-Ubeda, C., Skvortsova, K., Jimenez-Gancedo, S., Aldea, D., Marquez, Y., Buono, L., Kozmikova, I. & 41 othersPermanyer, J., Louis, A., Albuixech-Crespo, B., Le Petillon, Y., Leon Florian, A., Subirana, L., Balwierz, P. J., Duckett, P., Farahani, E., Aury, J. M., Mangenot, S., Wincker, P., Albalat, R., Benito-Gutierrez, E., Canestro, C., Castro, F., D'Aniello, S., Ferrier, D. E. K., Huang, S., Laudet, V., Marais, G., Pontarotti, P., Schubert, M., Seitz, H., Somorjai, I. M. L., Takahashi, T., Mirabeau, O., Xu, A., Yu, J-K., Carninci, P., Martinez-Morales, J., Crollius, H., Kozmik, Z., Weirauch, M., Garcia-Fernandez, J., Lister, R., Lenhard, B., Holland, P., Escriva, H., Gomez-Skarmeta, J. L. & Irimia, M., 21 Nov 2018, In : Nature. 564, 7734, p. 64-70 29 p.

    Research output: Contribution to journalArticle

  5. Horizons in evolutionary genomics: an interview with David Ferrier

    Ferrier, D. E. K., 1 Nov 2018, In : BMC Biology. 16, 3 p., 124.

    Research output: Contribution to journalArticle

ID: 26471701