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Research at St Andrews

Metabolic inhibitors of O-GlcNAc transferase (OGT) that act in vivo implicate decreased O-GlcNAc levels in leptin-mediated nutrient sensing

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  1. Linear Eyring plots conceal a change in rate-limiting step in an enzyme reaction

    Machado, T. F. G., Gloster, T. & da Silva, R. G., 11 Dec 2018, In : Biochemistry. 57, 49, p. 6757-6761

    Research output: Contribution to journalArticle

  2. New irreversible α-ʟ-iduronidase inhibitors and activity-based probes

    Artola, M., Kuo, C-L., McMahon, S. A., Oehler, V., Hansen, T., van der Lienden, M., He, X., van den Elst, H., Florea, B. I., Kermode, A. R., van der Marel, G. A., Gloster, T. M., Codée, J. D. C., Overkleeft, H. S. & Aerts, J. M. F. G., 26 Nov 2018, In : Chemistry - A European Journal. Early View, 9 p.

    Research output: Contribution to journalArticle

  3. Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

    Ren, W., Pengelly, R. J., Farren-Dai, M., Abadi, S. S. K., Oehler, V., Akintola, O., Draper, J., Meanwell, M., Chakladar, S., Swiderek, K., Moliner, V., Britton, R., Gloster, T. & Bennet, A., 13 Aug 2018, In : Nature Communications. 9, 12 p., 3243.

    Research output: Contribution to journalArticle

  4. The enzymatic degradation of heparan sulfate

    Griffin, L. S. & Gloster, T. M., 1 Aug 2017, In : Protein & Peptide Letters. 24, 8, p. 710-722

    Research output: Contribution to journalReview article

  5. Structural snapshots for mechanism-based inactivation of a glycoside hydrolase by cyclopropyl-carbasugars

    Adamson, C., Pengelly, R. J., Kazem Abadi, S. S., Chakladar, S., Draper, J., Britton, R., Gloster, T. M. & Bennet, A. J., 21 Nov 2016, In : Angewandte Chemie International Edition. 55, 48, p. 14978-14982

    Research output: Contribution to journalArticle

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  1. High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

    Iu, L., Fuentes, J. A., Janka, M., Fontenot, K. J. & Clarke, M. L., 11 Feb 2019, In : Angewandte Chemie International Edition. 58, 7, p. 2120-2124

    Research output: Contribution to journalArticle

  2. Metal-organic framework-activated carbon composite materials for the removal of ammonia from contaminated airstreams

    McHugh, L. N., Terracina, A., Wheatley, P. S., Buscarino, G., Smith, M. W. & Morris, R. E., 18 Jun 2019, (Accepted/In press) In : Angewandte Chemie International Edition. In press

    Research output: Contribution to journalArticle

  3. Visible light-promoted Fe-catalyzed C(sp2)-C(sp3) Kumada cross-coupling in flow

    Wei, X-J., Abdiaj, I., Sambiagio, C., Li, C., Zysman-Colman, E., Alcázar, J. & Noël, T., 11 Jul 2019, In : Angewandte Chemie International Edition. Early View, 6 p.

    Research output: Contribution to journalReview article

  4. Contra-thermodynamic, photocatalytic E→Z isomerization of styrenyl boron species: vectors to facilitate exploration of two-dimensional chemical space

    Molloy, J. J., Metternich, J. B., Daniliuc, C. G., Watson, A. J. B. & Gilmour, R., 12 Mar 2018, In : Angewandte Chemie International Edition. 57, 12, p. 3168-3172

    Research output: Contribution to journalArticle

  5. A C=O•••isothiouronium interaction dictates enantiodiscrimination in acylative kinetic resolution of tertiary heterocyclic alcohols

    Greenhalgh, M. D., Smith, S. M., Walden, D. M., Taylor, J. E., Brice, Z., Robinson, E. R. T., Fallan, C., Cordes, D. B., Slawin, A. M. Z., Richardson, H. C., Grove, M. A., Cheong, P. H-Y. & Smith, A. D., 12 Mar 2018, In : Angewandte Chemie International Edition. 57, 12, p. 3200-3206

    Research output: Contribution to journalArticle

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