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Microlaser-based contractility sensing in single cardiomyocytes and whole hearts

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

DOI

Author(s)

Marcel Schubert, Lewis Woolfson, Isla R.M. Barnard, Andrew Morton, Becky Casement, Gavin B. Robertson, Gareth B. Miles, Samantha J. Pitt, Carl S. Tucker, Malte C. Gather

School/Research organisations

Abstract

Microscopic whispering gallery mode lasers detect minute changes in cellular refractive index inside individual cardiac cells and in live zebrafish. We show that these signals encode cardiac contractility that can be used for intravital sensing.

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Details

Original languageEnglish
Title of host publicationNovel Biophotonics Techniques and Applications V
EditorsArjen Amelink, Seemantini K. Nadkarni
PublisherSPIE
ISBN (Electronic)9781510628434
DOIs
Publication statusPublished - 22 Jul 2019
EventNovel Biophotonics Techniques and Applications V 2019 - Munich, Germany
Duration: 26 Jun 2019 → 27 Jun 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11075
ISSN (Print)1605-7422

Conference

ConferenceNovel Biophotonics Techniques and Applications V 2019
CountryGermany
CityMunich
Period26/06/19 → 27/06/19

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ID: 263664849

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