Skip to content

Research at St Andrews

University > Research portal > Research publications > Mycobacterial load assay

Mycobacterial load assay

Research output: Chapter in Book/Report/Conference proceeding › Chapter

DOI

Open Access permissions

Open

Links

Author(s)

Stephen H Gillespie, Wilber Sabiiti, Katarina Oravcova

School/Research organisations

Abstract

Tuberculosis is a difficult disease to treat, a process made more harder as tools to monitor treatment response only provide a result long after the patient has provided a sample. The mycobacterial load assay (MBLA) provides a simple molecular test to quantify and determine the viability of M. tuberculosis in human or other samples.

Close
More...

Details

Original languageEnglish
Title of host publicationDiagnostic Bacteriology
Subtitle of host publicationMethods and Protocols
EditorsKimberley A. Bishop-Lilly
Place of PublicationNew York, NY
PublisherHumana Press/Springer
Pages89-105
Number of pages17
ISBN (Electronic)9781493970377
ISBN (Print)9781493970353
DOIs
Publication statusPublished - 2017

Publication series

NameMethods in Molecular Biology
Volume1616
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

    Research areas

  • Mycobacterial load assay (MBLA), Sputum, Ribosomal RNA (rRNA), Reverse transcriptase real-time quantitative polymerase chain reaction (RT-qPCR)

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Mycobactericidal effect of different regimens measured by molecular bacterial load assay among people treated for multidrug-resistant tuberculosis in Tanzania

    Mbelele, P. M., Mpolya, E. A., Sauli, E., Mtafya, B., Ntinginya, N. E., Addo, K. K., Kreppel, K., Mfinanga, S., Phillips, P. P. J., Gillespie, S. H., Heysell, S. K., Sabiiti, W. & Mpagama, S. G., 3 Feb 2021, In: Journal of Clinical Microbiology.

    Research output: Contribution to journal › Article › peer-review

  2. Tuberculosis bacillary load, an early marker of disease severity and treatment response: the utility of tuberculosis Molecular Bacterial Load Assay

    Sabiiti, W., Azam, K., Farmer, E., Kuchaka, D., Mtafya, B., Bowness, R., Oravcova, K., Honeyborne, I., Evangelopoulos, D., McHugh, T. D., Khosa, C., Rachow, A., Heinrich, N., Kampira, E., Davies, G., Bhatt, N., Ntinginya, E. N., Viegas, S., Jani, I., Kamdolozi, M. & 8 others, Mdolo, A., Khonga, M., Boeree, M. J., Phillips, P. PJ., Sloan, D. J., Hoelscher, M., Kibiki, G. & Gillespie, S. H., Jul 2020, In: Thorax. 75, 7, p. 606-608 3 p.

    Research output: Contribution to journal › Article › peer-review

  3. A tuberculosis molecular bacterial load assay (TB-MBLA)

    Sabiiti, W., Mtafya, B. A., Alferes De Lima, D., Dombay, E., Baron, V. O., Azam, K., Orascova, K., Sloan, D. J. & Gillespie, S. H., 30 Apr 2020, In: Journal of Visualized Experiments. 158, 10 p., e60460.

    Research output: Contribution to journal › Article › peer-review

  4. Model-based relationship between the molecular bacterial load assay and time-to-positivity in liquid culture

    Svensson, R. J., Sabiiti, W., Kibiki, G. S., Ntinginya, N. E., Bhatt, N., Davies, G., Gillespie, S. H. & Simonsson, U. S. H., Oct 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 15 p., e00652-19.

    Research output: Contribution to journal › Article › peer-review

  5. Molecular bacterial load assay (MBLA) concurs with culture on the NaOH-induced Mycobacterium tuberculosis loss of viability

    Mtafya, B., Sabiiti, W., Sabi, I., John, J., Sichone, E., Ntinginya, N. E. & Gillespie, S. H., 25 Jun 2019, In: Journal of Clinical Microbiology. 57, e01992-18.

    Research output: Contribution to journal › Article › peer-review

ID: 250685143

Top