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One-pot access to L-5,6-dihalotryptophans and L-alknyltryptophans using tryptophan synthase

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Michael J. Corr, Duncan R. M. Smith, Rebecca J. M. Goss

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We report, for the first time, the use of tryptophan synthase in the generation of L- dihalotryptophans and L-alkynyltryptophans. These previously unpublished compounds will be useful tools in the generation of probes for chemical biology, in biosynthetic diversification and as convenient building blocks for synthesis.


Original languageEnglish
Pages (from-to)7306-7310
Number of pages5
Issue number46
Early online date9 Feb 2016
StatePublished - 17 Nov 2016

    Research areas

  • Biotransformation, Dihalotryptophan, Alkynyltryptophan, Tryptophan synthase

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