Skip to content

Research at St Andrews

Operation Mechanism of a Molecular Machine Revealed Using Time-Resolved Vibrational Spectroscopy

Research output: Contribution to journalArticlepeer-review

DOI

Author(s)

Matthijs R. Panman, Pavol Bodis, Daniel J. Shaw, Bert H. Bakker, Arthur C. Newton, Euan Robert Kay, Albert M. Brouwer, Wybren Jan Buma, David A. Leigh, Sander Woutersen

School/Research organisations

Abstract

Rotaxanes comprise macrocycles that can shuttle between docking stations along an axle. We explored the nanosecond shuttling mechanism by reversing the relative binding affinities of two stations through ultraviolet-induced transient reduction. We monitored the ensuing changes in the CO-stretching bands of the two stations and the shuttling macrocycle by means of an infrared probing pulse. Because hydrogen-bond scission and formation at the initial and final stations led to well-resolved changes in the respective CO-stretch frequencies, the departure and arrival of the macrocycle could be observed separately. We found that the shuttling involves two steps: thermally driven escape from the initial station, followed by rapid motion along the track ending either at the initial or final station. By varying the track’s length, we found that the rapid motion approximates a biased one-dimensional random walk. However, surprisingly, the direction of the overall motion is opposite that of the bias.
Close

Details

Original languageEnglish
Pages (from-to)1255-1258
Number of pages4
JournalScience
Volume328
Issue number5983
DOIs
Publication statusPublished - 4 Jun 2010

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Programmable dynamic covalent nanoparticle building blocks with complementary reactivity

    Marro, N., della Sala, F. & Kay, E. R., 14 Jan 2020, In: Chemical Science. 11, 2, p. 372-383 12 p.

    Research output: Contribution to journalArticlepeer-review

  2. Probing the interaction of nanoparticles with small molecules in real time via quartz crystal microbalance monitoring

    Yang, Y., Poss, G., Weng, Y., Qi, R., Zheng, H., Nianias, N., Kay, E. R. & Guldin, S., 21 Jun 2019, In: Nanoscale. 11, 23, p. 11107-11113 7 p.

    Research output: Contribution to journalArticlepeer-review

  3. Twin-FRET: A New Molecular Ruler for Biomolecules

    Jana, S., Diez-Castellnou, M., Kay, E. R. & Penedo, C., 15 Feb 2019, In: Biophysical Journal. 116, 3, p. 565A-565A 1 p.

    Research output: Contribution to journalAbstractpeer-review

  4. Optical trapping of ultrasmooth gold nanoparticles in liquid and air

    Arita, Y., Tkachenko, G., McReynolds, N., Marro, N., Edwards, W., Kay, E. R. & Dholakia, K., 25 Jun 2018, In: APL Photonics. 3, 8 p., 070801.

    Research output: Contribution to journalArticlepeer-review

  5. Switchable selectivity within a series of boronate esters for dynamic covalent exchange in nonaqueous solvents

    Borsley, S., Poss, G., Spicer, R. L., Boudin, E. & Kay, E. R., 22 Feb 2018, In: Supramolecular Chemistry. Latest Articles, 10 p.

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. h/e oscillations in interlayer transport of delafossites

    Putzke, C., Bachmann, M. D., McGuinness, P., Zhakina, E., Sunko, V., Konczykowski, M., Oka, T., Moessner, R., Stern, A., König, M., Khim, S., Mackenzie, A. P. & Moll, P. J. W., 12 Jun 2020, In: Science. 368, 6496, p. 1234-1238 5 p.

    Research output: Contribution to journalArticlepeer-review

  2. An astronomically dated record of Earth's climate and its predictability over the last 66 million years

    Westerhold, T., Marwan, N., Drury, A. J., Liebrand, D., Agnini, C., Anagnostou, E., Barnet, J. S. K., Bohaty, S. M., De Vleeschouwer, D., Florindo, F., Frederichs, T., Hodell, D. A., Holbourn, A. E., Kroon, D., Lauretano, V., Littler, K., Lourens, L. J., Lyle, M., Pälike, H., Röhl, U. & 4 others, Tian, J., Wilkens, R. H., Wilson, P. A. & Zachos, J. C., 11 Sep 2020, In: Science. 369, 6509, p. 1383-1387 5 p.

    Research output: Contribution to journalArticlepeer-review

  3. Fire and biodiversity in the Anthropocene

    Kelly, L. T., Giljohann, K. M., Duane, A., Aquilué, N., Archibald, S., Batllori, E., Bennett, A. F., Buckland, S. T., Canelles, Q., Clarke, M. F., Fortin, M-J., Hermoso, V., Herrando, S., Keane, R. E., Lake, F. K., McCarthy, M. A., Morán-Ordóñez, A., Parr, C. L., Pausas, J. G., Penman, T. D. & 7 others, Regos, A., Rumpff, L., Santos, J. L., Smith, A. L., Syphard, A. D., Tingley, M. W. & Brotons, L., 20 Nov 2020, In: Science. 370, 6519, 11 p., eabb0355.

    Research output: Contribution to journalReview articlepeer-review

  4. Landscape-scale forest loss as a catalyst of population and biodiversity change

    Daskalova, G. N., Myers-Smith, I. H., Bjorkman, A. D., Blowes, S. A., Supp, S. R., Magurran, A. E. & Dornelas, M., 19 Jun 2020, In: Science. 368, 6497, p. 1341-1347 8 p.

    Research output: Contribution to journalArticlepeer-review

  5. Novel communities are a risky business

    Dornelas, M. & Madin, J. S., 9 Oct 2020, In: Science (New York, N.Y.). 370, 6513, p. 164-165 2 p.

    Research output: Contribution to journalComment/debatepeer-review

Related by journal

  1. Science (Journal)

    Craig Smeaton (Reviewer)

    7 Feb 2020 → …

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  2. Science (Journal)

    Will Cresswell (Reviewer)

    8 Mar 2018

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  3. Science (Journal)

    Anne Magurran (Member of editorial board)

    1 Jan 201831 Dec 2019

    Activity: Publication peer-review and editorial work typesEditor of research journal

  4. Science (Journal)

    Aileen Fyfe (Reviewer)

    6 Sep 2017

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  5. Science (Journal)

    Will Cresswell (Reviewer)

    6 Jul 2017

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

ID: 7439457

Top