Skip to content

Research at St Andrews

Phocine distemper Virus: current knowledge and future directions

Research output: Contribution to journalArticle

DOI

Open Access permissions

Open

Standard

Phocine distemper Virus : current knowledge and future directions. / Duignan, P.J.; Van Bressem, M.-F.; Baker, J.D.; Barbieri, M.; Colegrove, K.M.; de Guise, S.; de Swart, R.L.; di Guardo, G.; Dobson, A.; Duprex, W.P.; Early, G.; Fauquier, D.; Goldstein, T.; Goodman, S.J.; Grenfell, B.; Groch, K.R.; Gulland, F.; Hall, A.; Jensen, B.A.; Lamy, K.; Matassa, K.; Mazzariol, S.; Morris, S.E.; Nielsen, O.; Rotstein, D.; Rowles, T.K.; Saliki, J.T.; Siebert, U.; Waltzek, T.; Wellehan, J.F.

In: Viruses, Vol. 6, No. 12, 22.12.2014, p. 5093-5134.

Research output: Contribution to journalArticle

Harvard

Duignan, PJ, Van Bressem, M-F, Baker, JD, Barbieri, M, Colegrove, KM, de Guise, S, de Swart, RL, di Guardo, G, Dobson, A, Duprex, WP, Early, G, Fauquier, D, Goldstein, T, Goodman, SJ, Grenfell, B, Groch, KR, Gulland, F, Hall, A, Jensen, BA, Lamy, K, Matassa, K, Mazzariol, S, Morris, SE, Nielsen, O, Rotstein, D, Rowles, TK, Saliki, JT, Siebert, U, Waltzek, T & Wellehan, JF 2014, 'Phocine distemper Virus: current knowledge and future directions' Viruses, vol. 6, no. 12, pp. 5093-5134. https://doi.org/10.3390/v6125093

APA

Duignan, P. J., Van Bressem, M-F., Baker, J. D., Barbieri, M., Colegrove, K. M., de Guise, S., ... Wellehan, J. F. (2014). Phocine distemper Virus: current knowledge and future directions. Viruses, 6(12), 5093-5134. https://doi.org/10.3390/v6125093

Vancouver

Duignan PJ, Van Bressem M-F, Baker JD, Barbieri M, Colegrove KM, de Guise S et al. Phocine distemper Virus: current knowledge and future directions. Viruses. 2014 Dec 22;6(12):5093-5134. https://doi.org/10.3390/v6125093

Author

Duignan, P.J. ; Van Bressem, M.-F. ; Baker, J.D. ; Barbieri, M. ; Colegrove, K.M. ; de Guise, S. ; de Swart, R.L. ; di Guardo, G. ; Dobson, A. ; Duprex, W.P. ; Early, G. ; Fauquier, D. ; Goldstein, T. ; Goodman, S.J. ; Grenfell, B. ; Groch, K.R. ; Gulland, F. ; Hall, A. ; Jensen, B.A. ; Lamy, K. ; Matassa, K. ; Mazzariol, S. ; Morris, S.E. ; Nielsen, O. ; Rotstein, D. ; Rowles, T.K. ; Saliki, J.T. ; Siebert, U. ; Waltzek, T. ; Wellehan, J.F. / Phocine distemper Virus : current knowledge and future directions. In: Viruses. 2014 ; Vol. 6, No. 12. pp. 5093-5134.

Bibtex - Download

@article{09cb3e028bc948ceaed565dc9e9f0bdc,
title = "Phocine distemper Virus: current knowledge and future directions",
abstract = "Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.",
keywords = "Morbillivirus, Pinnipeds, Sea otter, CD150/SLAM, Phylogeny, Pathology, Epidemiology, Immunity, Vaccine",
author = "P.J. Duignan and {Van Bressem}, M.-F. and J.D. Baker and M. Barbieri and K.M. Colegrove and {de Guise}, S. and {de Swart}, R.L. and {di Guardo}, G. and A. Dobson and W.P. Duprex and G. Early and D. Fauquier and T. Goldstein and S.J. Goodman and B. Grenfell and K.R. Groch and F. Gulland and A. Hall and B.A. Jensen and K. Lamy and K. Matassa and S. Mazzariol and S.E. Morris and O. Nielsen and D. Rotstein and T.K. Rowles and J.T. Saliki and U. Siebert and T. Waltzek and J.F. Wellehan",
year = "2014",
month = "12",
day = "22",
doi = "10.3390/v6125093",
language = "English",
volume = "6",
pages = "5093--5134",
journal = "Viruses",
issn = "1999-4915",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "12",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Phocine distemper Virus

T2 - Viruses

AU - Duignan, P.J.

AU - Van Bressem, M.-F.

AU - Baker, J.D.

AU - Barbieri, M.

AU - Colegrove, K.M.

AU - de Guise, S.

AU - de Swart, R.L.

AU - di Guardo, G.

AU - Dobson, A.

AU - Duprex, W.P.

AU - Early, G.

AU - Fauquier, D.

AU - Goldstein, T.

AU - Goodman, S.J.

AU - Grenfell, B.

AU - Groch, K.R.

AU - Gulland, F.

AU - Hall, A.

AU - Jensen, B.A.

AU - Lamy, K.

AU - Matassa, K.

AU - Mazzariol, S.

AU - Morris, S.E.

AU - Nielsen, O.

AU - Rotstein, D.

AU - Rowles, T.K.

AU - Saliki, J.T.

AU - Siebert, U.

AU - Waltzek, T.

AU - Wellehan, J.F.

PY - 2014/12/22

Y1 - 2014/12/22

N2 - Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.

AB - Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years.

KW - Morbillivirus

KW - Pinnipeds

KW - Sea otter

KW - CD150/SLAM

KW - Phylogeny

KW - Pathology

KW - Epidemiology

KW - Immunity

KW - Vaccine

U2 - 10.3390/v6125093

DO - 10.3390/v6125093

M3 - Article

VL - 6

SP - 5093

EP - 5134

JO - Viruses

JF - Viruses

SN - 1999-4915

IS - 12

ER -

Related by author

  1. Mercury in cetaceans: exposure, bioaccumulation and toxicity

    Kershaw, J. & Hall, A., 30 Jul 2019, In : Science of the Total Environment. 694, p. 1-11 11 p., 133683.

    Research output: Contribution to journalReview article

  2. Age–length relationships in UK harbour seals during a period of population decline

    Hall, A. J., Mackey, B., Kershaw, J. L. & Thompson, P., 6 Sep 2019, In : Aquatic Conservation: Marine and Freshwater Ecosystems. 29, S1, p. 61-70 10 p.

    Research output: Contribution to journalArticle

  3. Investigating decadal changes in persistent organic pollutants in Scottish grey seal pups

    Robinson, K. J., Hall, A. J., Scholl, G., Debier, C., Thomé, J-P., Eppe, G., Adam, C. & Bennett, K. A., 6 Sep 2019, In : Aquatic Conservation: Marine and Freshwater Ecosystems. 29, S1, p. 86-100 15 p.

    Research output: Contribution to journalArticle

  4. Assessing cetacean body condition: is total lipid content in blubber biopsies a useful monitoring tool?

    Kershaw, J. L., Brownlow, A., Ramp, C. A., Miller, P. J. O. & Hall, A. J., 6 Sep 2019, In : Aquatic Conservation: Marine and Freshwater Ecosystems. 29, S1, p. 271-282 12 p.

    Research output: Contribution to journalArticle

  5. Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy

    McKnight, J. C., Bennett, K., Bronkhorst, M., Russell, D. JF., Balfour, S., Milne, R., Bivins, M., Moss, S. E. W., Colier, W., Hall, A. J. & Thompson, D., 18 Jun 2019, In : PLoS Biology. 17, 6, 20 p., e3000306.

    Research output: Contribution to journalArticle

Related by journal

  1. Viruses (Journal)

    Catherine S Adamson (Guest editor)
    Feb 2019Oct 2019

    Activity: Publication peer-review and editorial work typesEditor of research journal

  2. Viruses (Journal)

    Joanna Louise Parish (Editor)
    2009 → …

    Activity: Publication peer-review and editorial work typesEditor of research journal

Related by journal

  1. DNA‐Interacting characteristics of the archaeal Rudiviral protein SIRV2_Gp1

    Peeters, E., Boon, M., Rollie, C. J. C., Willaert, R. G., Voet, M., White, M. F., Prangishvili, D., Lavigne, R. & Quax, T. E. F., Jul 2017, In : Viruses. 9, 7, 13 p., 190.

    Research output: Contribution to journalArticle

  2. Cetacean morbillivirus: current knowledge and future directions

    Van Bressem, M-F., Duignan, P. J., Banyard, A., Barbieri, M., Colegrove, K. M., de Guise, S., di Guardo, G., Dobson, A., Domingo, M., Fauquier, D., Fernandez, A., Goldstein, T., Grenfell, B., Groch, K. R., Gulland, F., Jensen, B. A., Jepson, P. D., Hall, A., Kuiken, T., Mazzariol, S. & 12 othersMorris, S. E., Nielsen, O., Raga, J. A., Rowles, T. K., Saliki, J., Sierra, E., Stephens, N., Stone, B., Tomo, I., Wang, J., Waltzek, T. & Wellehan, J. F. X., 22 Dec 2014, In : Viruses. 6, 12, p. 5145-5181 37 p.

    Research output: Contribution to journalArticle

  3. Bunyaviruses and the type I interferon system

    Elliott, R. M. & Weber, F., 23 Nov 2009, In : Viruses. 1, 3, p. 1003-1021

    Research output: Contribution to journalArticle

ID: 161866991