Skip to content

Research at St Andrews

Purifying selection in corvids is less efficient on islands

Research output: Contribution to journalArticlepeer-review

DOI

Open Access permissions

Open

Author(s)

Verena E. Kutschera, Jelmer W. Poelstra, Fidel Botero-Castro, Nicolas Dussex, Neil J. Gemmell, Gavin R. Hunt, Michael G. Ritchie, Christian Rutz, R. Axel W. Wiberg, Jochen B.W. Wolf

School/Research organisations

Abstract

Theory predicts that deleterious mutations accumulate more readily in small populations. As a consequence, mutation load is expected to be elevated in species where life-history strategies and geographic or historical contingencies reduce the number of reproducing individuals. Yet, few studies have empirically tested this prediction using genome-wide data in a comparative framework. We collected whole-genome sequencing data for 147 individuals across seven crow species (Corvus spp.). For each species, we estimated the distribution of fitness effects of deleterious mutations and compared it with proxies of the effective population size Ne. Island species with comparatively smaller geographic range sizes had a significantly increased mutation load. These results support the view that small populations have an elevated risk of mutational meltdown, which may contribute to the higher extinction rates observed in island species.
Close

Details

Original languageEnglish
Pages (from-to)469-474
Number of pages6
JournalMolecular Biology and Evolution
Volume37
Issue number2
Early online date21 Oct 2019
DOIs
Publication statusPublished - Feb 2020

    Research areas

  • Avian genomics, Comparative analysis, Distribution of fitness effects, Molecular evolution, Mutation load, Selection

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. A genome-wide investigation of adaptive signatures in protein-coding genes related to tool behaviour in New Caledonian and Hawaiian crows

    Dussex, N., Kutschera, V. E., Wiberg, R. A. W., Parker, D. J., Hunt, G. R., Gray, R. D., Rutherford, K., Abe, H., Fleischer, R. C., Ritchie, M. G., Rutz, C., B.Wolf, J. & Gemmell, N. J., Feb 2021, In: Molecular Ecology. 30, 4, p. 973-986

    Research output: Contribution to journalArticlepeer-review

  2. Raptor research during the COVID-19 pandemic provides invaluable opportunities for conservation biology

    Sumasgutner, P., Buij, R., McClure, C. J. W., Shaw, P., Dykstra, C. R., Kumar, N. & Rutz, C., 28 Apr 2021, In: Biological Conservation. 109149.

    Research output: Contribution to journalArticlepeer-review

  3. A deepening understanding of animal culture suggests lessons for conservation

    Brakes, P., Carroll, E. L., Dall, S., Keith, S., McGregor, P., Mesnick, S., Noad, M., Rendell, L., Robbins, M., Rutz, C., Thorton, A., Whiten, A., Whiting, M., Aplin, L., Bearhop, S., Ciucci, P., Fishlock, V., Ford, J., Notarbartolo di Sciara, G., Simmonds, M. & 5 others, Spina, F., Wade, P., Whithead, H., Williams, J. & Garland, E. C., 28 Apr 2021, In: Proceedings of the Royal Society B: Biological Sciences. 288, 1949, 10 p., 20202718.

    Research output: Contribution to journalReview articlepeer-review

  4. A standardisation framework for bio-logging data to advance ecological research and conservation

    Sequeira, A. M. M., O’Toole, M., Keates, T. R., McDonnell, L. H., Braun, C. D., Hoenner, X., Jaine, F. R. A., Jonsen, I. D., Newman, P., Pye, J., Bograd, S. J., Hays, G. C., Hazen, E. L., Holland, M., Tsontos, V., Blight, C., Cagnacci, F., Davidson, S. C., Dettki, H., Duarte, C. M. & 22 others, Dunn, D. C., Eguíluz, V. M., Fedak, M., Gleiss, A. C., Hammerschlag, N., Hindell, M. A., Holland, K., Janekovic, I., McKinzie, M. K., Muelbert, M. M. C., Pattiaratchi, C., Rutz, C., Sims, D. W., Simmons, S. E., Townsend, B., Whoriskey, F., Woodward, B., Costa, D. P., Heupel, M. R., McMahon, C. R., Harcourt, R. & Weise, M., 1 Apr 2021, In: Methods in Ecology and Evolution. Early View

    Research output: Contribution to journalArticlepeer-review

  5. Experimental evolution supports signatures of sexual selection in genomic divergence

    Wiberg, R. A. W., Veltsos, P., Snook, R. & Ritchie, M. G., 22 Mar 2021, In: Evolution Letters. Early View, 16 p., 220.

    Research output: Contribution to journalArticlepeer-review

Related by journal

  1. Molecular Biology and Evolution (Journal)

    Carolin Kosiol (Member of editorial board)

    2018 → …

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Related by journal

  1. Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses

    Kapun, M., Barrón, M. G., Staubach, F., Obbard, D. J., Wiberg, R. A. W., Vieira, J., Goubert, C., Rota-Stabelli, O., Kankare, M., Bogaerts-Márquez, M., Haudry, A., Waidele, L., Kozeretska, I., Pasyukova, E. G., Loeschcke, V., Pascual, M., Vieira, C. P., Serga, S., Montchamp-Moreau, C., Abbott, J. & 25 others, Gibert, P., Porcelli, D., Posnien, N., Sánchez-Gracia, A., Grath, S., Sucena, É., Bergland, A. O., Guerreiro, M. P. G., Onder, B. S., Argyridou, E., Guio, L., Schou, M. F., Deplancke, B., Vieira, C., Ritchie, M. G., Zwaan, B. J., Tauber, E., Orengo, D. J., Puerma, E., Aguadé, M., Schmidt, P., Parsch, J., Betancourt, A. J., Flatt, T. & González, J., 1 Sep 2020, In: Molecular Biology and Evolution. 37, 9, p. 2661-2678 18 p.

    Research output: Contribution to journalArticlepeer-review

  2. MicroRNA clusters integrate evolutionary constraints on expression and target affinities: the miR-6/5/4/286/3/309 cluster in Drosophila

    Qu, Z., Yiu, W. C., Yip, H. Y., Nong, W., Yu, C. W. C., Lee, I. H. T., Wong, A. Y. P., Wong, N. W. Y., Cheung, F. K. M., Chan, T. F., Lau, K. F., Zhong, S., Chu, K. H., Tobe, S. S., Ferrier, D. E. K., Bendena, W. G. & Hui, J. H. L., Oct 2020, In: Molecular Biology and Evolution. 37, 10, p. 2955-2965 msaa146.

    Research output: Contribution to journalArticlepeer-review

  3. More than one-to-four via 2R: evidence of an independent amphioxus expansion and two-gene ancestral vertebrate state for MyoD-related Muscle Regulatory Factors (MRFs)

    Aase-Remedios, M. E., Coll-Lladó, C. & Ferrier, D. E. K., Oct 2020, In: Molecular Biology and Evolution. 37, 10, p. 2966-2982 17 p.

    Research output: Contribution to journalArticlepeer-review

  4. Polymorphism-aware species trees with advanced mutation models, bootstrap and rate heterogeneity

    Schrempf, D., Minh, B. Q., von Haeseler, A. & Kosiol, C., Jun 2019, In: Molecular Biology and Evolution. 36, 6, p. 1294-1301 8 p.

    Research output: Contribution to journalArticlepeer-review

ID: 266390213

Top