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Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway

Research output: Contribution to journal › Article

DOI

Author(s)

Andrew Riches, Elaine Campbell, Eva Borger, Simon Powis

School/Research organisations

Abstract

Exosomes are small 50-100nm sized extracellular vesicles released from normal and tumour cells and are a source of a new intercellular communication pathway. Tumour exosomes promote tumour growth and progression. What regulates the release and homoeostatic levels of exosomes, in cancer, in body fluids remains undefined.
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Details

Original languageEnglish
Pages (from-to)1025-34
Number of pages10
JournalEuropean Journal of Cancer
Volume50
Issue number5
Early online date24 Jan 2014
DOIs
Publication statusPublished - Mar 2014

    Research areas

  • Blotting, Western, Breast Neoplasms, Cell Line, Tumor, Cells, Cultured, Epithelial Cells, Exosomes, Extracellular Space, Female, Fluorescent Dyes, Humans, Mammary Glands, Human, Microscopy, Confocal, Organic Chemicals, Signal Transduction, Time Factors

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