Skip to content

Research at St Andrews

Selective NaOH-catalysed hydration of aromatic nitriles to amides

Research output: Contribution to journalArticle

DOI

Open Access permissions

Open

Author(s)

Thibault Schmid, Alberto Gomez Herrera, Olivier Songis, Deborah Sneddon , Antoine Révolte , Fady Nahra, Catherine S.J. Cazin

School/Research organisations

Abstract

The selective synthesis of aromatic and heteroaromatic amides through base-catalysed hydration of nitriles was achieved using inexpensive and commercially available NaOH as the only catalyst. A wide range of nitriles was selectively converted to their corresponding amides. Kinetic studies show that the double hydration of nitriles towards undesirable carboxylic acids is negligible under our reaction conditions.
Close

Details

Original languageEnglish
Pages (from-to)2865-2868
JournalCatalysis Science & Technology
Volume5
Issue number5
Early online date24 Mar 2015
DOIs
Publication statusPublished - 1 May 2015

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by journal

  1. Effect of oxygen coordination environment of Ca-Mn oxides on catalytic performance of Pd supported catalysts for aerobic oxidation of 5-hydroxymethyl-2-furfural

    Yang, J., Yu, H., Wang, Y., Qi, F., Liu, H., Lou, L-L., Yu, K., Zhou, W. & Liu, S., 7 Dec 2019, In : Catalysis Science & Technology. 9, 23, p. 6659-6668

    Research output: Contribution to journalArticle

  2. Photoredox catalysts based on Earth-abundant metal complexes

    Hockin, B., Li, C., Robertson, N. & Zysman-Colman, E., 21 Feb 2019, In : Catalysis Science & Technology. 9, 4, p. 889-915

    Research output: Contribution to journalArticle

  3. Less hindered ligands give improved catalysts for the nickel catalysed Grignard cross-coupling of aromatic ethers

    Harkness, G. J. & Clarke, M. L., 7 Jan 2018, In : Catalysis Science & Technology. 8, 1, p. 328-334

    Research output: Contribution to journalArticle

  4. M3+O(-Mn4+)2 clusters in doped MnOx catalysts as promoted active sites for aerobic oxidation of 5-hydroxymethylfurfural

    Yu, K., Liu, Y., Lei, D., Jiang, Y., Wang, Y., Feng, Y., Lou, L-L., Liu, S. & Zhou, W., 7 May 2018, In : Catalysis Science & Technology. 8, 9, p. 2299-2303

    Research output: Contribution to journalReview article

ID: 175341936

Top