Skip to content

Research at St Andrews

The First Myriapod Genome Sequence Reveals Conservative Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima

Research output: Contribution to journalArticle

Author(s)

Ariel D Chipman, David E K Ferrier, Carlo Brena, Jiaxin Qu, Daniel S T Hughes, Reinhard Schröder, Montserrat Torres-Oliva, Nadia Znassi, Huaiyang Jiang, Francisca C Almeida, Claudio R Alonso, Zivkos Apostolou, Peshtewani Aqrawi, Wallace Arthur, Jennifer C J Barna, Kerstin P Blankenburg, Daniela Brites, Salvador Capella-Gutiérrez, Marcus Coyle, Peter K Dearden & 86 others Louis Du Pasquier, Elizabeth J Duncan, Dieter Ebert, Cornelius Eibner, Galina Erikson, Peter D Evans, Cassandra G Extavour, Liezl Francisco, Toni Gabaldón, William J Gillis, Elizabeth A Goodwin-Horn, Jack E Green, Sam Griffiths-Jones, Cornelis J P Grimmelikhuijzen, Sai Gubbala, Roderic Guigó, Yi Han, Frank Hauser, Paul Havlak, Luke Hayden, Sophie Helbing, Michael Holder, Jerome H L Hui, Julia P Hunn, Vera S Hunnekuhl, LaRonda Jackson, Mehwish Javaid, Shalini N Jhangiani, Francis M Jiggins, Tamsin E Jones, Tobias S Kaiser, Divya Kalra, Nathan J Kenny, Viktoriya Korchina, Christie L Kovar, F Bernhard Kraus, François Lapraz, Sandra L Lee, Jie Lv, Christigale Mandapat, Gerard Manning, Marco Mariotti, Robert Mata, Tittu Mathew, Tobias Neumann, Irene Newsham, Dinh N Ngo, Maria Ninova, Geoffrey Okwuonu, Fiona Ongeri, William J Palmer, Shobha Patil, Pedro Patraquim, Christopher Pham, Ling-Ling Pu, Nicholas H Putman, Catherine Rabouille, Olivia Mendivil Ramos, Adelaide C Rhodes, Helen E Robertson, Hugh M Robertson, Matthew Ronshaugen, Julio Rozas, Nehad Saada, Alejandro Sánchez-Gracia, Steven E Scherer, Andrew M Schurko, Kenneth W Siggens, DeNard Simmons, Anna Stief, Eckart Stolle, Maximilian J Telford, Kristin Tessmar-Raible, Rebecca Thornton, Maurijn van der Zee, Arndt von Haeseler, James M Williams, Judith H Willis, Yuanqing Wu, Xiaoyan Zou, Daniel Lawson, Donna M Muzny, Kim C Worley, Richard A Gibbs, Michael Akam, Stephen Richards

School/Research organisations

Abstract

Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda is the only arthropod class not represented by a sequenced genome. We present an analysis of the genome of the centipede Strigamia maritima. It retains a compact genome that has undergone less gene loss and shuffling than previously sequenced arthropods, and many orthologues of genes conserved from the bilaterian ancestor that have been lost in insects. Our analysis locates many genes in conserved macro-synteny contexts, and many small-scale examples of gene clustering. We describe several examples where S. maritima shows different solutions from insects to similar problems. The insect olfactory receptor gene family is absent from S. maritima, and olfaction in air is likely effected by expansion of other receptor gene families. For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where insects use alternate splicing. This is most striking for the Dscam gene, which in Drosophila generates more than 100,000 alternate splice forms, but in S. maritima is encoded by over 100 paralogues. We see an intriguing linkage between the absence of any known photosensory proteins in a blind organism and the additional absence of canonical circadian clock genes. The phylogenetic position of myriapods allows us to identify where in arthropod phylogeny several particular molecular mechanisms and traits emerged. For example, we conclude that juvenile hormone signalling evolved with the emergence of the exoskeleton in the arthropods and that RR-1 containing cuticle proteins evolved in the lineage leading to Mandibulata. We also identify when various gene expansions and losses occurred. The genome of S. maritima offers us a unique glimpse into the ancestral arthropod genome, while also displaying many adaptations to its specific life history.
Close

Details

Original languageEnglish
Article numbere1002005
Number of pages24
JournalPLoS Biology
Volume12
Issue number11
DOIs
Publication statusPublished - Nov 2014

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. Space and time in Hox/ParaHox gene cluster evolution.

    Ferrier, D. E. K., 2019, Perspectives on Evolutionary Developmental Biology: Essays for Alessandro Minelli. Fusco, G. (ed.). Padova: Padova University Press, p. 245-258

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. Two more Posterior Hox genes and Hox cluster dispersal in echinoderms

    Szabó, R. & Ferrier, D. E. K., 27 Dec 2018, In : BMC Evolutionary Biology. 18, 13 p., 203.

    Research output: Contribution to journalArticle

  3. Transcriptional regulation of the Ciona Gsx gene in the neural plate

    Hudson, C., Esposito, R., Palladino, A., Staiano, L., Ferrier, D., Faure, E., Lemaire, P., Yasuo, H. & Spagnuolo, A., 21 Dec 2018, In : Developmental Biology. In press

    Research output: Contribution to journalArticle

  4. Amphioxus functional genomics and the origins of vertebrate gene regulation

    Marletaz, F., Firbas, P., Maeso, I., Tena, J., Bogdanovic, O., Perry, M., Wyatt, C., de la Calle-Mustienes, E., Bertrand, S., Burguera, D., Acemel, R., van Heeringen, S., Naranjo, S., Herrera-Ubeda, C., Skvortsova, K., Jimenez-Gancedo, S., Aldea, D., Marquez, Y., Buono, L., Kozmikova, I. & 41 othersPermanyer, J., Louis, A., Albuixech-Crespo, B., Le Petillon, Y., Leon Florian, A., Subirana, L., Balwierz, P. J., Duckett, P., Farahani, E., Aury, J. M., Mangenot, S., Wincker, P., Albalat, R., Benito-Gutierrez, E., Canestro, C., Castro, F., D'Aniello, S., Ferrier, D. E. K., Huang, S., Laudet, V., Marais, G., Pontarotti, P., Schubert, M., Seitz, H., Somorjai, I. M. L., Takahashi, T., Mirabeau, O., Xu, A., Yu, J-K., Carninci, P., Martinez-Morales, J., Crollius, H., Kozmik, Z., Weirauch, M., Garcia-Fernandez, J., Lister, R., Lenhard, B., Holland, P., Escriva, H., Gomez-Skarmeta, J. L. & Irimia, M., 21 Nov 2018, In : Nature. 564, 7734, p. 64-70 29 p.

    Research output: Contribution to journalArticle

  5. Horizons in evolutionary genomics: an interview with David Ferrier

    Ferrier, D. E. K., 1 Nov 2018, In : BMC Biology. 16, 3 p., 124.

    Research output: Contribution to journalArticle

Related by journal

  1. Bonobo and chimpanzee gestures overlap extensively in meaning

    Graham, K. E., Hobaiter, C., Ounsley, J., Furuichi, T. & Byrne, R. W., 27 Feb 2018, In : PLoS Biology. 16, 2, 18 p., e2004825.

    Research output: Contribution to journalArticle

  2. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain

    Albuixech-Crespo, B., López-Blanch, L., Burguera, D., Maeso, I., Sánchez Arrones, L., Moreno-Bravo, J. A., Somorjai, I., Pascual-Anaya, J., Puelles, E., Bovolenta, P., Garcia-Fernàndez, J., Puelles, L., Irimia, M. & Ferran, J. L., 19 Apr 2017, In : PLoS Biology. 15, 4, 34 p., e2001573.

    Research output: Contribution to journalArticle

  3. An estimate of the total DNA in the biosphere

    Landenmark, H. K. E., Forgan, D. H. & Cockell, C. S., 11 Jun 2015, In : PLoS Biology. 13, 6, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  4. Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages

    Sarkies, P., Selkirk, M. E., Jones, J. T., Blok, V., Boothby, T., Goldstein, B., Hanelt, B., Ardila-Garcia, A., Fast, N. M., Schiffer, P. M., Kraus, C., Taylor, M. J., Koutsovoulos, G., Blaxter, M. L. & Miska, E. A., 10 Feb 2015, In : PLoS Biology. 13, 2, 20 p., e1002061.

    Research output: Contribution to journalArticle

  5. Evolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus

    Laabei, M., Uhlemann, A-C., Lowy, F. D., Austin, E. D., Yokoyama, M., Ouadi, K., Feil, E., Thorpe, H. A., Williams, B., Perkins, M., Peacock, S. J., Clarke, S. R., Dordel, J., Holden, M., Votintseva, A. A., Bowden, R., Crook, D. W., Young, B. C., Wilson, D. J., Recker, M. & 1 othersMassey, R. C., 2 Sep 2015, In : PLoS Biology. 13, 9, 21 p., e1002229.

    Research output: Contribution to journalArticle

Related by journal

  1. PLoS Biology (Journal)

    Sophie Caroline Smout (Reviewer)
    1 Apr 201730 Apr 2017

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

  2. PLoS Biology (Journal)

    Sophie Caroline Smout (Reviewer)
    20112012

    Activity: Publication peer-review and editorial work typesPeer review of manuscripts

ID: 158364333