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The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode

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The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. / Cotton, James A.; Lilley, Catherine J.; Jones, Laura M.; Kikuchi, Taisei; Reid, Adam J.; Thorpe, Peter; Tsai, Isheng J.; Beasley, Helen; Blok, Vivian; Cock, Peter J. A.; Eves-van den Akker, Sebastian; Holroyd, Nancy; Hunt, Martin; Mantelin, Sophie; Naghra, Hardeep; Pain, Arnab; Palomares-Rius, Juan E.; Zarowiecki, Magdalena; Berriman, Matthew; Jones, John T.; Urwin, Peter E.

In: Genome Biology, Vol. 15, No. 3, R43, 03.03.2014.

Research output: Contribution to journalArticle

Harvard

Cotton, JA, Lilley, CJ, Jones, LM, Kikuchi, T, Reid, AJ, Thorpe, P, Tsai, IJ, Beasley, H, Blok, V, Cock, PJA, Eves-van den Akker, S, Holroyd, N, Hunt, M, Mantelin, S, Naghra, H, Pain, A, Palomares-Rius, JE, Zarowiecki, M, Berriman, M, Jones, JT & Urwin, PE 2014, 'The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode' Genome Biology, vol. 15, no. 3, R43. https://doi.org/10.1186/gb-2014-15-3-r43

APA

Cotton, J. A., Lilley, C. J., Jones, L. M., Kikuchi, T., Reid, A. J., Thorpe, P., ... Urwin, P. E. (2014). The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. Genome Biology, 15(3), [R43]. https://doi.org/10.1186/gb-2014-15-3-r43

Vancouver

Cotton JA, Lilley CJ, Jones LM, Kikuchi T, Reid AJ, Thorpe P et al. The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. Genome Biology. 2014 Mar 3;15(3). R43. https://doi.org/10.1186/gb-2014-15-3-r43

Author

Cotton, James A. ; Lilley, Catherine J. ; Jones, Laura M. ; Kikuchi, Taisei ; Reid, Adam J. ; Thorpe, Peter ; Tsai, Isheng J. ; Beasley, Helen ; Blok, Vivian ; Cock, Peter J. A. ; Eves-van den Akker, Sebastian ; Holroyd, Nancy ; Hunt, Martin ; Mantelin, Sophie ; Naghra, Hardeep ; Pain, Arnab ; Palomares-Rius, Juan E. ; Zarowiecki, Magdalena ; Berriman, Matthew ; Jones, John T. ; Urwin, Peter E. / The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. In: Genome Biology. 2014 ; Vol. 15, No. 3.

Bibtex - Download

@article{fceea2bfde6547bfa3261912b19ed8aa,
title = "The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode",
abstract = "Background: Globodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of cyst nematodes. Cyst nematodes and root-knot nematodes are the two most important plant parasitic nematode groups and together represent a global threat to food security. Results: We present the complete genome sequence of G. pallida, together with transcriptomic data from most of the nematode life cycle, particularly focusing on the life cycle stages involved in root invasion and establishment of the biotrophic feeding site. Despite the relatively close phylogenetic relationship with root-knot nematodes, we describe a very different gene family content between the two groups and in particular extensive differences in the repertoire of effectors, including an enormous expansion of the SPRY domain protein family in G. pallida, which includes the SPRYSEC family of effectors. This highlights the distinct biology of cyst nematodes compared to the root-knot nematodes that were, until now, the only sedentary plant parasitic nematodes for which genome information was available. We also present in-depth descriptions of the repertoires of other genes likely to be important in understanding the unique biology of cyst nematodes and of potential drug targets and other targets for their control. Conclusions: The data and analyses we present will be central in exploiting post-genomic approaches in the development of much-needed novel strategies for the control of G. pallida and related pathogens.",
keywords = "Double-stranded-rna, Caenorhabditis-elegans, Heterodera-glycines, Karyotype analysis, Meloidogyne-hapla",
author = "Cotton, {James A.} and Lilley, {Catherine J.} and Jones, {Laura M.} and Taisei Kikuchi and Reid, {Adam J.} and Peter Thorpe and Tsai, {Isheng J.} and Helen Beasley and Vivian Blok and Cock, {Peter J. A.} and {Eves-van den Akker}, Sebastian and Nancy Holroyd and Martin Hunt and Sophie Mantelin and Hardeep Naghra and Arnab Pain and Palomares-Rius, {Juan E.} and Magdalena Zarowiecki and Matthew Berriman and Jones, {John T.} and Urwin, {Peter E.}",
note = "Date of Acceptance: 03/03/2014",
year = "2014",
month = "3",
day = "3",
doi = "10.1186/gb-2014-15-3-r43",
language = "English",
volume = "15",
journal = "Genome Biology",
issn = "1465-6906",
publisher = "BioMed Central",
number = "3",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode

AU - Cotton, James A.

AU - Lilley, Catherine J.

AU - Jones, Laura M.

AU - Kikuchi, Taisei

AU - Reid, Adam J.

AU - Thorpe, Peter

AU - Tsai, Isheng J.

AU - Beasley, Helen

AU - Blok, Vivian

AU - Cock, Peter J. A.

AU - Eves-van den Akker, Sebastian

AU - Holroyd, Nancy

AU - Hunt, Martin

AU - Mantelin, Sophie

AU - Naghra, Hardeep

AU - Pain, Arnab

AU - Palomares-Rius, Juan E.

AU - Zarowiecki, Magdalena

AU - Berriman, Matthew

AU - Jones, John T.

AU - Urwin, Peter E.

N1 - Date of Acceptance: 03/03/2014

PY - 2014/3/3

Y1 - 2014/3/3

N2 - Background: Globodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of cyst nematodes. Cyst nematodes and root-knot nematodes are the two most important plant parasitic nematode groups and together represent a global threat to food security. Results: We present the complete genome sequence of G. pallida, together with transcriptomic data from most of the nematode life cycle, particularly focusing on the life cycle stages involved in root invasion and establishment of the biotrophic feeding site. Despite the relatively close phylogenetic relationship with root-knot nematodes, we describe a very different gene family content between the two groups and in particular extensive differences in the repertoire of effectors, including an enormous expansion of the SPRY domain protein family in G. pallida, which includes the SPRYSEC family of effectors. This highlights the distinct biology of cyst nematodes compared to the root-knot nematodes that were, until now, the only sedentary plant parasitic nematodes for which genome information was available. We also present in-depth descriptions of the repertoires of other genes likely to be important in understanding the unique biology of cyst nematodes and of potential drug targets and other targets for their control. Conclusions: The data and analyses we present will be central in exploiting post-genomic approaches in the development of much-needed novel strategies for the control of G. pallida and related pathogens.

AB - Background: Globodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of cyst nematodes. Cyst nematodes and root-knot nematodes are the two most important plant parasitic nematode groups and together represent a global threat to food security. Results: We present the complete genome sequence of G. pallida, together with transcriptomic data from most of the nematode life cycle, particularly focusing on the life cycle stages involved in root invasion and establishment of the biotrophic feeding site. Despite the relatively close phylogenetic relationship with root-knot nematodes, we describe a very different gene family content between the two groups and in particular extensive differences in the repertoire of effectors, including an enormous expansion of the SPRY domain protein family in G. pallida, which includes the SPRYSEC family of effectors. This highlights the distinct biology of cyst nematodes compared to the root-knot nematodes that were, until now, the only sedentary plant parasitic nematodes for which genome information was available. We also present in-depth descriptions of the repertoires of other genes likely to be important in understanding the unique biology of cyst nematodes and of potential drug targets and other targets for their control. Conclusions: The data and analyses we present will be central in exploiting post-genomic approaches in the development of much-needed novel strategies for the control of G. pallida and related pathogens.

KW - Double-stranded-rna

KW - Caenorhabditis-elegans

KW - Heterodera-glycines

KW - Karyotype analysis

KW - Meloidogyne-hapla

U2 - 10.1186/gb-2014-15-3-r43

DO - 10.1186/gb-2014-15-3-r43

M3 - Article

VL - 15

JO - Genome Biology

T2 - Genome Biology

JF - Genome Biology

SN - 1465-6906

IS - 3

M1 - R43

ER -

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ID: 208028097