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Research at St Andrews

The Histone Chaperones Nap1 and Vps75 Bind Histones H3 and H4 in a Tetrameric Conformation

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  1. Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

    Kapsalis, C., Wang, B., El Mkami, H., Pitt, S. J., Schnell, J., Smith, T. K., Lippiat, J., Bode, B. E. & Pliotas, C., 10 Oct 2019, In : Nature Communications. 10, 14 p., 4619.

    Research output: Contribution to journalArticle

  2. A gadolinium spin label with both a narrow central transition and short tether for use in double electron electron resonance distance measurements

    Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G., Parker, D. & Lovett, J. E., 18 Feb 2019, In : Inorganic Chemistry. Article ASAP

    Research output: Contribution to journalArticle

  3. Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

    Sundaramoorthy, R., Hughes, A. L., El-Mkami, H., Norman, D. G., Ferreira, H. & Owen-Hughes, T., 6 Aug 2018, In : eLife. 7, 28 p., e35720.

    Research output: Contribution to journalArticle

  4. Distance measurement of a noncovalently bound Y@C82 Pair with double electron electron resonance spectroscopy

    Gil-Ramírez, G., Shah, A., El Mkami, H., Porfyrakis, K., Briggs, A. D., Morton, J. J. L., Anderson, H. L. & Lovett, J. E., 20 Jun 2018, In : Journal of the American Chemical Society. 140, 24, p. 7420-7424

    Research output: Contribution to journalArticle

  5. Cryo-EM structure of a relaxase reveals the molecular basis of DNA unwinding during bacterial conjugation

    Ilangovan, A., Kay, C. W. M., Roier, S., El Mkami, H., Salvadori, E., Zechner, E. L., Zanetti, G. & Waksman, G., 4 May 2017, In : Cell. 169, 4, p. 708-721 27 p., e12.

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  1. Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signalling after nuclear DNA damage

    Dunphy, G., Flannery, S. M., Almine, J. F., Connolly, D. J., Paulus, C., Jonsson, K. L., Jakobsen, M. R., Nevels, M. M., Bowie, A. G. & Unterholzner, L., 6 Sep 2018, In : Molecular Cell. 71, 5, p. 745-760 22 p., e5.

    Research output: Contribution to journalArticle

  2. Structure of the CRISPR Interference complex CSM reveals key similarities with Cascade

    Rouillon, C., Zhou, M., Zhang, J., Argyris, P., Beilsten-Edmands, V., Cannone, G., Graham, S., Robinson, C., Spagnolo, L. & White, M. F., 10 Oct 2013, In : Molecular Cell. 52, 1, p. 124-134 11 p.

    Research output: Contribution to journalArticle

  3. Structure and mechanism of the CMR complex for CRISPR-Mediated antiviral immunity

    Zhang, J., Rouillon, C., Kerou, M., Reeks, J., Brugger, K., Graham, S., Reimann, J., Cannone, G., Liu, H., Albers, S-V., Naismith, J. H., Spagnolo, L. & White, M. F., 10 Feb 2012, In : Molecular Cell. 45, 3, p. 303-313 11 p.

    Research output: Contribution to journalArticle

  4. ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance.

    Parish, J. L., Bean, AM., Park, RB. & Androphy, EJ., 28 Dec 2006, In : Molecular Cell. 24, 6, p. 867-876 10 p.

    Research output: Contribution to journalArticle

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