Skip to content

Research at St Andrews

The relationship between cancer patient's fear of recurrence and radiotherapy: a systematic review and meta-analysis

Research output: Research - peer-reviewReview article

DOI

Open Access permissions

Open

Abstract

OBJECTIVE: This review aims to provide an overview of the current knowledge available on the nature and extent of the relationship between external-beam radiotherapy (RT) and fear of cancer recurrence (FoR).

METHODS: PubMed, MEDLINE and EMBASE databases were searched to identify relevant studies. Systematic review procedures were followed including a quality assessment. Meta-analysis of suitable studies was conducted.

RESULTS: Twenty-five eligible studies were included in the systematic review and 15 of them were included in further meta-analysis. Meta-analysis of the available data confirmed a weak relationship between RT and FoR (15 studies, 9567 patients, overall r = 0.053, 95%, CI: 0.021-0.085, P = 0.001). Subgroup analysis based on cancer site (breast cancer versus other types of cancer) revealed that the correlation between RT and FoR was statistically significant in 'other cancer' group (P˂0.001) but was nonsignificant in 'breast cancer' group (P = 0.538).

CONCLUSIONS: While meta-analysis reports a statistically significant association between cancer patient's FoR and the receipt of RT, these results should be interpreted with caution due to significant variability between studies. Further longitudinal studies should be conducted to address the trajectory of FoR over RT in greater detail. 

Close

Details

Original languageEnglish
Pages (from-to)738-746
Number of pages9
JournalPsycho-Oncology
Volume26
Issue number6
Early online date10 Aug 2016
DOIs
StatePublished - Jun 2017

    Research areas

  • Radiotherapy, Fear of recurrence, Cancer, Oncology, Meta-analysis

Discover related content
Find related publications, people, projects and more using interactive charts.

View graph of relations

Related by author

  1. A single session intervention (The Mini AFTERc) for fear of cancer recurrence: a feasibility study

    Davidson, J., Malloch, M. & Humphris, G. 30 Apr 2018 In : Psycho-Oncology. Early View

    Research output: Research - peer-reviewArticle

  2. Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: a cluster preference randomized controlled trial

    Rogers, S. N., Lowe, D., Lowies, C., Yeo, S. T., Allmark, C., Mcavery, D., Humphris, G. M., Flavel, R., Semple, C., Thomas, S. J. & Kanatas, A. 18 Apr 2018 In : BMC Cancer. 18, 10 p., 444

    Research output: Research - peer-reviewArticle

  3. Multimorbidity and socioeconomic deprivation in primary care consultations

    Mercer, S. W., Zhou, Y., Humphris, G. M., McConnachie, A., Bakhshi, A., Bikker, A., Higgins, M., Little, P., Fitzpatrick, B. & Watt, G. C. M. Mar 2018 In : Annals of Family Medicine. 16, 2, p. 127-131 5 p.

    Research output: Research - peer-reviewArticle

Related by journal

  1. A single session intervention (The Mini AFTERc) for fear of cancer recurrence: a feasibility study

    Davidson, J., Malloch, M. & Humphris, G. 30 Apr 2018 In : Psycho-Oncology. Early View

    Research output: Research - peer-reviewArticle

  2. Current state and future prospects of research on fear of cancer recurrence

    Lebel, S., Ozakinci, G., Humphris, G., Thewes, B., Prins, J., Dinkel, A. & Butow, P. Apr 2017 In : Psycho-Oncology. 26, 4, p. 424-427 4 p.

    Research output: Research - peer-reviewEditorial

  3. Barriers and Facilitators to smoking cessation: A qualitative study of patients', family members' and professionals' views in a cancer context

    Wells, M., Aitchison, P., Harris, F., Ozakinci, G., Bauld, L., Entwistle, V., Munro, A., Haw, S., Williams, B. & Radley, A. Oct 2016 In : Psycho-Oncology. 25, SP. S3, p. 167-168 2 p.

    Research output: Research - peer-reviewAbstract

  4. Neglected domains of fears of cancer recurrence research and future directions

    Ozakinci, G. Oct 2016 In : Psycho-Oncology. 25, SP. S3, p. 82-84 3 p.

    Research output: Research - peer-reviewAbstract

Related by journal

  1. Psycho-Oncology (Journal)

    Ozakinci, G. (Reviewer)
    2011 → …

    Activity: Publication peer-review and editorial workPeer review of manuscripts

ID: 244565795