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The Urbilaterian Super-Hox cluster.

Research output: Contribution to journalArticle

Author(s)

T Butts, PWH Holland, David Ellard Keith Ferrier

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Abstract

Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

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Original languageEnglish
Pages (from-to)259 - 262
Number of pages4
JournalTrends in Genetics
Volume24
Issue number6
DOIs
StatePublished - Jun 2008

    Research areas

  • HOMEOBOX GENE CLUSTERS, NEMATOSTELLA-VECTENSIS, PARAHOX GENES, EVOLUTION, AMPHIOXUS, PHYLOGENY, EVX

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