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Understanding 'non-genetic' inheritance: insights from molecular-evolutionary crosstalk

Research output: Contribution to journalReview articlepeer-review

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Understanding 'non-genetic' inheritance : insights from molecular-evolutionary crosstalk. / Adrian-Kalchhauser, Irene; Sultan, Sonia E.; Shama, Lisa N.S.; Spence-Jones, Helen Clare; Tiso, Stefano; Keller Valsecchi, Claudia Isabelle; Weissing, Franz J.

In: Trends in Ecology & Evolution, Vol. 35, No. 12, 12.2020, p. 1078-1089.

Research output: Contribution to journalReview articlepeer-review

Harvard

Adrian-Kalchhauser, I, Sultan, SE, Shama, LNS, Spence-Jones, HC, Tiso, S, Keller Valsecchi, CI & Weissing, FJ 2020, 'Understanding 'non-genetic' inheritance: insights from molecular-evolutionary crosstalk', Trends in Ecology & Evolution, vol. 35, no. 12, pp. 1078-1089. https://doi.org/10.1016/j.tree.2020.08.011

APA

Adrian-Kalchhauser, I., Sultan, S. E., Shama, L. N. S., Spence-Jones, H. C., Tiso, S., Keller Valsecchi, C. I., & Weissing, F. J. (2020). Understanding 'non-genetic' inheritance: insights from molecular-evolutionary crosstalk. Trends in Ecology & Evolution, 35(12), 1078-1089. https://doi.org/10.1016/j.tree.2020.08.011

Vancouver

Adrian-Kalchhauser I, Sultan SE, Shama LNS, Spence-Jones HC, Tiso S, Keller Valsecchi CI et al. Understanding 'non-genetic' inheritance: insights from molecular-evolutionary crosstalk. Trends in Ecology & Evolution. 2020 Dec;35(12):1078-1089. https://doi.org/10.1016/j.tree.2020.08.011

Author

Adrian-Kalchhauser, Irene ; Sultan, Sonia E. ; Shama, Lisa N.S. ; Spence-Jones, Helen Clare ; Tiso, Stefano ; Keller Valsecchi, Claudia Isabelle ; Weissing, Franz J. / Understanding 'non-genetic' inheritance : insights from molecular-evolutionary crosstalk. In: Trends in Ecology & Evolution. 2020 ; Vol. 35, No. 12. pp. 1078-1089.

Bibtex - Download

@article{5a9e065b67874e2bb30bafb4bc0eb486,
title = "Understanding 'non-genetic' inheritance: insights from molecular-evolutionary crosstalk",
abstract = "Understanding the evolutionary and ecological roles of 'non-genetic' inheritance(NGI) is daunting due to the complexity and diversity of epigenetic mechanisms.We draw on insights from molecular and evolutionary biology perspectives toidentify three general features of 'non-genetic' inheritance systems: (i) they arefunctionally interdependent with, rather than separate from, DNA sequence; (ii)precise mechanisms vary phylogenetically and operationally; and (iii) epigeneticelements are probabilistic, interactive regulatory factors and not deterministic'epialleles' with defined genomic locations and effects. We discuss each ofthese features and offer recommendations for future empirical and theoreticalresearch that implements a unifying inherited gene regulation (IGR) approachto studies of 'non-genetic' inheritance.",
keywords = "Epigenetics, Extended inheritance, Epiallelic variation, Theoretical models, Transgenerational effects, Inherited gene regulation",
author = "Irene Adrian-Kalchhauser and Sultan, {Sonia E.} and Shama, {Lisa N.S.} and Spence-Jones, {Helen Clare} and Stefano Tiso and {Keller Valsecchi}, {Claudia Isabelle} and Weissing, {Franz J.}",
note = "The idea for this paper was initially proposed by I.A.-K. and was further developed by all authors in a workshop generously funded by grant No 789240 from the European Research Council (ERC) to F.J.W. S.E.S. acknowledges support from Wesleyan University and The John Templeton Foundation.",
year = "2020",
month = dec,
doi = "10.1016/j.tree.2020.08.011",
language = "English",
volume = "35",
pages = "1078--1089",
journal = "Trends in Ecology and Evolution",
issn = "0169-5347",
publisher = "ELSEVIER SCIENCE LONDON",
number = "12",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Understanding 'non-genetic' inheritance

T2 - insights from molecular-evolutionary crosstalk

AU - Adrian-Kalchhauser, Irene

AU - Sultan, Sonia E.

AU - Shama, Lisa N.S.

AU - Spence-Jones, Helen Clare

AU - Tiso, Stefano

AU - Keller Valsecchi, Claudia Isabelle

AU - Weissing, Franz J.

N1 - The idea for this paper was initially proposed by I.A.-K. and was further developed by all authors in a workshop generously funded by grant No 789240 from the European Research Council (ERC) to F.J.W. S.E.S. acknowledges support from Wesleyan University and The John Templeton Foundation.

PY - 2020/12

Y1 - 2020/12

N2 - Understanding the evolutionary and ecological roles of 'non-genetic' inheritance(NGI) is daunting due to the complexity and diversity of epigenetic mechanisms.We draw on insights from molecular and evolutionary biology perspectives toidentify three general features of 'non-genetic' inheritance systems: (i) they arefunctionally interdependent with, rather than separate from, DNA sequence; (ii)precise mechanisms vary phylogenetically and operationally; and (iii) epigeneticelements are probabilistic, interactive regulatory factors and not deterministic'epialleles' with defined genomic locations and effects. We discuss each ofthese features and offer recommendations for future empirical and theoreticalresearch that implements a unifying inherited gene regulation (IGR) approachto studies of 'non-genetic' inheritance.

AB - Understanding the evolutionary and ecological roles of 'non-genetic' inheritance(NGI) is daunting due to the complexity and diversity of epigenetic mechanisms.We draw on insights from molecular and evolutionary biology perspectives toidentify three general features of 'non-genetic' inheritance systems: (i) they arefunctionally interdependent with, rather than separate from, DNA sequence; (ii)precise mechanisms vary phylogenetically and operationally; and (iii) epigeneticelements are probabilistic, interactive regulatory factors and not deterministic'epialleles' with defined genomic locations and effects. We discuss each ofthese features and offer recommendations for future empirical and theoreticalresearch that implements a unifying inherited gene regulation (IGR) approachto studies of 'non-genetic' inheritance.

KW - Epigenetics

KW - Extended inheritance

KW - Epiallelic variation

KW - Theoretical models

KW - Transgenerational effects

KW - Inherited gene regulation

U2 - 10.1016/j.tree.2020.08.011

DO - 10.1016/j.tree.2020.08.011

M3 - Review article

VL - 35

SP - 1078

EP - 1089

JO - Trends in Ecology and Evolution

JF - Trends in Ecology and Evolution

SN - 0169-5347

IS - 12

ER -

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